Spiders Blight damage reduced
Spiders do not scale crit or damage between apprentice and veteran difficulties
Spider Spit reduces protection instead of accuracy
Formless Head's Maws of Life lowered chance of gaining an extra target at veteran and champion difficulties
Formless Butt's Undalating Invasion Accuracy reduced by 10 and damage reduced
Formless Flesh's will now very likely drop a trinket like other bosses
Bosses are now guaranteed to drop a trinket

Gems are looted more commonly
Gold is looted less commonly
The more dangerous Courtyard monsters (Manservant, Chevalier, Esquire and Courtesans) drop more loot
Sanguine Snuff Craving hasten reduced
Double Edged Pendant Max HP buff removed
Sycophant's Bombing Run damage reduced by 25%
Esquire's Needling Execration no longer causes stress
Courtesan's Renewed Appetite no longer causes stress
Fanatic's Pyre has 10 less health while a hero is captured (scaled to later variations)
Fanatic's Righteous Condemnation reworked to grant Prot per target hit (overall protection granted lowered)
Stress dealt by all of the Fanatics skill has been decreased
The Fanatic cannot cast Sentence Rendered immediately if a captor has been quickly released
Fanatic's stun resist has been reduced by 25%
Fanatic's Blight and Debuff resistance reduced by 15%

Occultist update - See change log for full details
Decrepify changed to Empyrean Gaze
Vulnerablility Hex changed to Binding Ward
Hands from the Abyss changed to Abyssal Anchor

Jester's Finale Dodge debuff reduced in length
Grave Robber's Poison Darts can now be used from the back position

Medical Kits nnow cure Blight and Bleed
All hero specific ancestral trinkets have had their sell prices increased dramatically
Arbalest's Bola hit chance reduced by 10

Bad Gambler Crit reduction reduced by 2
Hellion no longer double heals with Adrenaline Rush
Evasive Dodge buff reduced by 3