If you like rpg, sandbox, and hardcore survival games, then Kenshi is for you.

What's great:
-The limb system. Your characters don't just have health bars like most other games, rather every limb has its own health bar. The armor you wear has more of a difference than just a higher rating, you also have to make sure it covers parts of the body for defense. And, if you lose a limb, it's gone unless you can get a replacement, and losing a limb can seriously hinder your character especially if you lose a leg. If you're in combat and your head, stomach, or chest get too heavily injured your character is knocked unconscious and has to wait for it to recover before getting back up.
-Food. It's simple, just have food in your character's inventory and they'll eat it on their own. If they're well fed they'll be fine, but if they don't eat enough they get stat penalties and can eventually starve to death, and if their hunger goes too low they can pass out and won't do anything, leaving you helpless if you don't have others in your group.
-Combat. It has different animations, the attacks are mostly random in what limb they hit, and there's different ways to play when it comes to what kind of combat your character does from crossbows to swords to martial arts or a mix of them.
-Base building. You can make your own base out in the world, or settle in a town, or do whatever. It's your story to forge. You can set up multiple bases too as needed to get all the resources you'll need as different areas have different levels of water, fertility, iron, copper, etc that you will need to thrive. Plus, you will have occasional visits from trade caravans, warbands, religious zealots, etc who will all have their own events that you have to deal with which can range from simple to possibly death depending on which it is.
-Weapons. There's a good amount of weapons that have different classes. Each class of weapons has different uses that could be a benefit or hindrance depending on where you go.

Again, it's really there for if you want hardcore survival rpg sandbox. It's a hard game when you first start and are unsure of how everything works.

EDIT: I forgot to add the inventory system for the game before. The inventory doesn't work as each item taking up a single slot, but each item has a size to it, making you have to sort things out to fit more if you want. If you want to carry a lot of stuff, you need to invest in ways of increasing how much you can carry like a backpack or animal, which have their own penalties to keep in mind.

It's a great system, with the only modern game I can think of that has it being Escape from Tarkov. It's an underused inventory system in survival games and other games in general even.