That could happen? Win the lottery.

I like being told I am doing a good job, especially when I am having a hard day

I guess I am a simple person

Free games for life.

A place of my own that the house, heck even trailer home is paid for and utility's are cheap, instead of renting

I could finish the grand project give it away to humanity's gamers and then some aliens take me into space and I get to watch space and its wonders as my last moments.

- this would be a process of some time like years mind.

alien invasion with a cryptid landing party

Of course money, needless to say my excessive desire always pushes it away, because life hates the needy apparently

To continue as is, then die peacefully in my sleep right before my health begins to seriously deteriorate.

Dying in infancy.

whatever it is, it's taken for granted

I quote liked getting a pet dog at age 12, it made a huge change overall... both with responsibly and empathy towards others.

To crush my enemies, see them driven before me and to hear the lamentation of their women.

Originally posted by GustavoM:

What is the best thing that could ever happen in your life?

There's a couple of rather large ambiguities in your question.
1. "ever happen in your life" - like... ever, in the entire span of it, or right in this moment?
2. What do you mean by "could" as theoretical physics sort of "could", or just what's feasible?

Theoretically, the best thing that could probably happen in my life is if I'd gotten a manual / guide book from my future self as a child (by about age 6) about the dos and do nots and unexpected pitfalls and convergent outcomes.

Less theoretically, the best thing that could happen in the years ahead of me is technology & service availability to improve my health and life-span significantly, by oh... idk... maybe a few thousand years...

Feasibly, without projecting societal improvements that might not happen...
Well,

• Unrealistically, I somehow am given a rather nice house, somewhere far away from where I live now but would like to move to, with my own workshop, half a million dollars (don't really need a million, tbh), where I quickly meet the significant other of my dreams and just live well.
  
• Realistically in the future : I meet a significant other that fits what I'm looking for and is well off enough that I can move in with her.
  
• Theoretically realistically right now : An old friend that I don't have issues with, shows up at my door unexpectedly and offers to take me to some kind of social event where I might meet new people and have a good time. (But that's not going to happen. Such surprises don't happen.)
  
• Semi-realistically right now : I finish my to-do list, and somehow have sudden bursts of inspiration that cause me to write down the exact right things and register the exact right accounts so that tomorrow my dreams don't have to stay dreams. But this requires mental insights that I just don't have right now.
  
• Still not quite realistic enough : I find one of my two misplaced harmonicas and actually make some progress learning it.
  
• Realistically : I finish my to-do list for the day with a few extra minor accomplishments, have a nice chat with someone, 1 small serendipitous thing happens, I make 1 small change to my life that somehow improves the course of my entire future, I go to bed not feeling miserable and actually enjoy a video game for a change.

...at least that's just what I can think of. Perhaps more accurately, it would be something I wouldn't even consider that just suddenly appears.

Best thing that could happen in my life is if I became one with the goofy goobers down in bikini bottom and live my dream of going to weenie hut jr jr and being the best sea creature in bikini bottom, but then turn into a savage shark and then start eating all the spongebob and friends

For the entire human civilization to go back to "Mother Nature"... or something like that.