In order to prevent the score from being affected by Mods and Assets, I compared almost in the vanilla setting.
All assets are Disabled.
However, for benchmarking, Enable several Mods.

I searched and downloaded vanilla SAVEDATAS which does not require DLC, MOD or ASSET from Workshop.
(Savedatas Population Over 100,000, Over 240,000, Over 380,000)
However, I have enabled all DLC except Radio DLC.

Back up the current settings, Then turn off all Mods, Assets, District styles.
The procedure is in the guide below.
https://gtm.steamproxy.vip/sharedfiles/filedetails/?id=1592205761

2-1: Go to Workshop and subscribe to the following Mods.
2-2: Enable these four Mods in the Content Manager.

Mods Listing (Save and load mods config)
https://gtm.steamproxy.vip/sharedfiles/filedetails/?id=588691634
FPS Display
https://gtm.steamproxy.vip/sharedfiles/filedetails/?id=407683828
Simulation Speed Benchmark
https://gtm.steamproxy.vip/sharedfiles/filedetails/?id=908700552
Loading Screen Mod [Test]
https://gtm.steamproxy.vip/sharedfiles/filedetails/?id=833779378

2-3: Subscribe and Enable following Save datas.

• Yeol's Brussels (100.000 citizens)
  
• https://gtm.steamproxy.vip/sharedfiles/filedetails/?id=428526154

• Rockfield
  
• https://gtm.steamproxy.vip/sharedfiles/filedetails/?id=620682016

• David's City #7 (380K citizens, big industry & commercial, no traffic jam)
  
• https://gtm.steamproxy.vip/sharedfiles/filedetails/?id=646954846

After loading the data, I went to a specific place on the map and got scores in the distance view and close view.
These were Benchmarked after standing for 1 minute at Speed: x1 at each measurement location.

=======================================
Yeol's Brussels
Population: 103,849





Distant view PC1 Simulation Speed: 19.7 - 14.7
Distant view PC1 fps: 14.7 - 20.9
Close view PC1 Simulation Speed: 16.4 - 16.5
Close view PC1 fps: 10.4 - 11.3

Distant view PC2 Simulation Speed: 7.7 - 7.7
Distant view PC2 fps: 40.1 - 41.0
Close view PC2 Simulation Speed: 8.1 - 8.3
Close view PC2 fps: 23.8 - 24.0

Distant view PC2-2 Simulation Speed: 8.1 - 8.4
Distant view PC2-2 fps: 30.1 - 32.8
Close view PC2-2 Simulation Speed: 8.8 - 9.1
Close view PC2-2 fps: 18.7 - 19.6

Distant view PC2-3 Simulation Speed: 7.9 - 7.9
Distant view PC2-3 fps: 12.7 - 13.9
Close view PC2-3 Simulation Speed: 8.3 - 8.6
Close view PC2-3 fps: 10.9 - 11.2

=======================================
Rockfield
Population: 241,058





Distant view PC2 Simulation Speed: 11.1 - 11.1
Distant view PC2 fps: 35.4 - 35.5
Close view PC2 Simulation Speed: 11.4 - 11.4
Close view PC2 fps: 24.6 - 24.7

Distant view PC2-2 Simulation Speed: 10.6 - 10.8
Distant view PC2-2 fps: 25.7 -25.9
Close view PC2-2 Simulation Speed: 11.2 - 11.2
Close view PC2-2 fps: 9.4 - 9.9

=======================================
David's City #7
Population: 384,848





Distant view PC2 Simulation Speed: 12.3 - 12.3
Distant view PC2 fps: 34.9 - 35.2
Close view PC2 Simulation Speed: 13.0 - 13.0
Close view PC2 fps: 26.8 - 27.0

MB: msi H55-GD65 (INTEL/H55)
CPU: intel Core i7 870 (2.93GHz) 4core 8threads
VGA: ZOTAC GTX 770 (2GB)
RAM: DDR3 4GB*4 (16GB)
SSD: SanDisk SDSSDH3

MB: msi Z390-A PRO (INTEL/Z390)
CPU: intel Core i5 9600K (3.7GHz-4.4GHz) 6core 6threads
VGA: msi GTX 1070 GAMING X (8GB)
RAM: DDR4 16GB*2 (32GB)
SSD: SanDisk SDSSDH3

PC1 and PC2-1 Used Memory
Cities.exe - Commit(KB):10,346,456 - Working Set(KB):4,743,644

Same system as PC2-1 (With 33Mods[gist.github.com] and 6 assets by NE2)
PC2-2 Used Memory
Cities.exe - Commit(KB):14,994,272 - Working Set(KB):6,595,064

Same system as PC2-1 (With 62Mods[gist.github.com] and 6 assets by NE2)
PC2-3 Used Memory
Cities.exe - Commit(KB):15,397,656 - Working Set(KB):7,076,940