Curare (/kʊˈrɑ:ri/ or /kjʊˈrɑ:ri/; kuu-RAH-ree or kyuu-RAH-ree) is a common name for various alkaloid arrow poisons originating from plant extracts. Used as a paralyzing agent by indigenous peoples in Central and South America for hunting and for therapeutic purposes, curare only becomes active when it contaminates a wound or is introduced directly to the bloodstream; it is not active when ingested orally.

Curare is prepared by boiling the bark of one of the dozens of plant sources, leaving a dark, heavy paste that can be applied to arrow or dart heads.

These poisons cause weakness of the skeletal muscles and, when administered in a sufficient dose, eventual death by asphyxiation due to paralysis of the diaphragm. In medicine, curare has been used as a treatment for tetanus and strychnine poisoning and as a paralyzing agent for surgical procedures.

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⢸
⢸
⢸⡀⠀⠀⠀⠀⠀⠀⠀⠀⣠⣶⣿⣶⣄
⢿⣿⣄⠀⠀⠀⠀⠀⠀⠀⣿⣿⣿⣿⣿⠀⠀⠀⠀⠀⠀⠀⠀⣀⣤⣄
⠀⠹⣿⣧⣀⣠⣴⣾⣷⣿⣷⠾⢷⠋⠀⠀⠀⠀⠀⠀⠀⣼⣿⣿⣿⡷
⠀⠀⠈⢿⡿⠟⢻⣿⣿⣿⣿⣿⣿⣷⠀⠀⠀⠀⠀⠀⠀⠹⣿⣿⣿⡟
⠀⠀⠀⠀⠀⠀⣼⣿⣿⣿⣿⣿⡟⢿⣿⣄⠀⠀⠀⠀⢠⣶⣾⣿⡇
⠀⠀⠀⠀⠀⠀⣿⣿⣿⣿⣿⣿⡇⠀⠙⠿⡿⢆⣴⣿⣿⣿⣿⡇
⠀⠀⠀⠀⠀⢰⣿⣿⣿⣿⣿⣿⠀⠀⣤⣶⣾⣿⣿⣿⣿⣷⠹⣷⣤⣤⣄⣀⡀
⠀⠀⠀⠀⠀⢸⣿⣿⡏⣿⣿⣿⢀⣾⣿⣿⣿⣿⣏⠀⠀⢀⣀⣈⣉⣉⣉⣙⣁⣀
⠀⠀⠀⠀⠀⢸⣿⣿⡇⣿⣿⢏⣾⣿⣿⣿⣿⣿⣿⣆
⠀⠀⠀⠀⠀⢸⣿⣿⡇⣿⣿⣷⠈⠉⠙⠛⢻⣭⣷
⠀⠀⠀⠀⠀⢸⣿⣿⡇⣿⣿⣿⠀⠀⠀⠀⠀⢹⣿⣷
⠀⠀⠀⠀⠀⢸⣿⣿⡇⣿⣿⣿⠀⠀⠀⠀⠀⣾⣿⡏
⠀⠀⠀⠀⠀⢸⣿⣿⡇⣿⣿⣿⠀⠀⠀⠀⢰⣿⣿
⠀⠀⠀⠀⠀⠘⢿⡿⠇⠻⣿⠟⠀⠀⠀⠀⢿⣿⠇

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⣿⣿⣻⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿
⣿⣵⣿⣿⣿⠿⡟⣛⣧⣿⣯⣿⣝⡻⢿⣿⣿⣿⣿⣿
⣿⣿⣿⠋⠁⣴⣶⣿⣿⣿⣿⣿⣿⣿⣦⣍⢿⣿⣿⣿
⣿⣿⢷⠄⣾⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣏⢼⣿⣿
⣿⢻⠎⠔⣛⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⡏⣿⣿
⣿⠇⡶⠄⣿⣿⠿⠟⡛⠛⠻⣿⡿⠿⠿⣿⣗⢣⣿⣿
⣿⡿⣷⣾⣿⣿⣿⣾⣶⣶⣶⣿⣁⣔⣤⣀⣼⢲⣿⣿
⣿⣿⣿⣾⣟⣿⣿⣿⣿⣿⣿⣿⡿⣿⣿⣿⢟⣾⣿⣿
⣿⣿⣿⡷⣿⣿⣿⣿⣿⣮⣽⠛⢻⣽⣿⡇⣾⣿⣿⣿
⣿⣿⣿⡷⠻⢻⡻⣯⣝⢿⣟⣛⣛⣛⠝⢻⣿⣿⣿⣿
⣿⣿⡟⣹⣦⠄⠋⠻⢿⣶⣶⣶⡾⠃⡂⢾⣿⣿⣿⣿
⠟⠋⠄⢻⣿⣧⣲⡀⡀⠄⠉⠱⣠⣾⡇⠄⠉⠛⢿⣿
⠄⠄⠄⠈⣿⣿⣿⣷⣿⣿⢾⣾⣿⣿⣇⠄⠄⠄⠄⠄
⠄⠄⠄⠄⠸⣿⣿⠟⠃⠄⠄⢈⣻⣿⣿⠄⠄⠄⠄⠄
⠄⠄⠄⠄⠄⢿⣿⣾⣷⡄⠄⢾⣿⣿⣿⡄⠄⠄⠄⠄
⠄⠄⠄⠄⠄⠸⣿⣿⣿⠃⠄⠈⢿⣿⣿⠄⠄⠄⠄⠄\

⣿⣿⠏⣠⣾⣦⡐⢌⢿⣷⣦⣅⡑⠕⠡⠐⢿⠿⣛⠟⠛⠛⠛⠛⠡⢷⡈⢂⢕
⠟⣡⣾⣿⣿⣿⣿⣦⣑⠝⢿⣿⣿⣿⣿⣿⡵⢁⣤⣶⣶⣿⢿⢿⢿⡟⢻⣤⢑
⣾⣿⣿⡿⢟⣛⣻⣿⣿⣿⣦⣬⣙⣻⣿⣿⣷⣿⣿⢟⢝⢕⢕⢕⢕⢽⣿⣿⣷
⣿⣿⠵⠚⠉⢀⣀⣀⣈⣿⣿⣿⣿⣿⣿⣿⣿⣿⣗⢕⢕⢕⢕⢕⢕⣽⣿⣿⣿
⢷⣂⣠⣴⣾⡿⡿⡻⡻⣿⣿⣴⣿⣿⣿⣿⣿⣿⣷⣵⣵⣵⣷⣿⣿⣿⣿⣿⣿
⢌⠻⣿⡿⡫⡪⡪⡪⡪⣺⣿⣿⣿⣿⣿⠿⠿⢿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿
⠣⡁⠹⡪⡪⡪⡪⣪⣾⣿⣿⣿⣿⠋⠐⢉⢍⢄⢌⠻⣿⣿⣿⣿⣿⣿⣿⣿⠏
⡣⡘⢄⠙⣾⣾⣾⣿⣿⣿⣿⣿⣿⡀⢐⢕⢕⢕⢕⢕⡘⣿⣿⣿⣿⣿⣿⠏⠠
⠌⢊⢂⢣⠹⣿⣿⣿⣿⣿⣿⣿⣿⣧⢐⢕+rep ⢕⢅⣿⣿⣿⣿⡿⢋⢜⠠
⠄⠁⠕⢝⡢⠈⠻⣿⣿⣿⣿⣿⣿⣿⣷⣕⣑⣑⣑⣵⣿⣿⣿⡿⢋⢔⢕⣿⠠
⠨⡂⡀⢑⢕⡅⠂⠄⠉⠛⠻⠿⢿⣿⣿⣿⣿⣿⣿⣿⣿⡿⢋⢔⢕⢕⣿⣿⠠

⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⠿⠿⠿⠿⠿⠿⢿⣿⣿⣿⣿⣿⣿⣿⣿
⣿⣿⣿⣿⣿⣿⣿⠟⣉⡥⠶⢶⣿⣿⣿⣿⣷⣆⠉⠛⠿⣿⣿⣿⣿⣿
⣿⣿⣿⣿⣿⡿⢡⡞⠁⠀⠀⠤⠈⠿⠿⠿⠿⣿⠀⢻⣦⡈⠻⣿⣿⣿
⣿⣿⣿⣿⣿⡇⠘⡁⠀⢀⣀⣀⣀⣈⣁⣐⡒⠢⢤⡈⠛⢿⡄⠻⣿⣿
⣿⣿⣿⣿⣿⡇⠀⢀⣼⣿⣿⣿⣿⣿⣿⣿⣿⣶⣄⠉⠐⠄⡈⢀⣿⣿
⣿⣿⣿⣿⣿⠇⢠⣿⣿⣿⣿⡿⢿⣿⣿⣿⠁⢈⣿⡄⠀⢀⣀⠸⣿⣿
⣿⣿⡿⠟⣡⣶⣶⣬⣭⣥⣴⠀⣾⣿⣿⣿⣶⣾⣿⣧⠀⣼⣿⣷⣌⡻
⠟⣋⣴⣾⣿⣿⣿⣿⣿⣿⣿⡇⢿⣿+rep⣿⣿⡿⢸⣿⣿⣿⣿⣷
⢾⣿⣿⣿⣿⣿⣿⣿⣿⣿⡿⠟⢂⣭⣿⣿⣿⣿⣿⠇⠘⠛⠛⢉⣉⣠
⣦⣬⣍⣉⣉⣛⣛⣉⠉⣤⣶⣾⣿⣿⣿⣿⣿⣿⡿⢰⣿⣿⣿⣿⣿⣿
⣿⣿⣿⣿⣿⣿⣿⣿⣧⡘⣿⣿⣿⣿⣿⣿⣿⣿⡇⣼⣿⣿⣿⣿⣿⣿
⣿⣿⣿⣿⣿⣿⣿⣿⣿⣇⢸⣿⣿⣿⣿⣿⣿⣿⠁⣿⣿⣿⣿⣿⣿⣿