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Symptoms of syphilis:
The first stage involves a painless sore on the genitals, rectum, or mouth. After the initial sore heals, the second stage is characterized by a rash. Then, there are no symptoms until the final stage which may occur years later. This final stage can result in damage to the brain, nerves, eyes, or heart.
Basically, she might start to recieve brain damage towards the end of her term.
If not, then maybe in her second term in the rare event she'll get elected twice.