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Short description:
Repentogon is for Rep (base Repentance), not Rep+. In Steam, go to Properties → DLC and disable Rep+. Then install and run Repentogon on base Rep (follow the Repentogon installation guide).
to bring the save back into rep+:
in steam on isaac properties → general → disable cloud saving.
go to stats page hit alt + f2 go into a new run press c and choose your option
go to Documents\My Games\Binding of Isaac Repentance copy your save file (will look like this 20251012.rep_persistentgamedata1.dat)
go to C\Steam\userdata\<yourSteamID>\250900\remote\ and clear it.
drop your save in there as rep+persistentgamedata1.dat (exact name).
launch once to confirm.
re-enable cloud and choose upload local to cloud.