For my manual to work you need.

5x Mob justice! (on higher lvl, wave 40+ nothing else work as good as angry mob )
10 x Epic Reduce charge cost (to ensure best cost reduction)
LVL 5 weapon in all heroes (to be able place rune i right wave )
Full upgraded Town Hall (lvl 15) (to improve Mob dmg)

Now the rule how Angry mob travel
!! Angry mob will travel on path from which last wave was release !!

example

On map you have Green a Yellow path. Last wave was realese from Green path this is patch wich will take Angry mob. That mean if you have trouble on Green path and last wave came from Yellow path angry mob will not help you.

This rule is very important in map like Chapel or Cemetery.

In addition of previews must list this thing will help you. Mostly in early waves.

Fully upgraded Forge (lvl 15)
Fully upgraded weapons (lvl 8)
Heroes whit all maximum skill (+ lvl 73 for Jack +lvl 70 for rest

Epick Soul Reaper runes and Barrage runes

Best way how t to get money for your runes a upgrades is Castle Garden map

On hard difficulty whit challenge tower defense you get 15 gem and around 3000 gold per game.
Game length is around 4 minutes (whit double speed)

This why you also get nice amount of experience around 20 000 I thing.

In every hero you place rune like this


Position of first reduce charge cost dos not matter.
Position of second Reduce charge cost is fundamental.

Without reduce charge rune in 5 slot whit Mob justice! You will don’t get 30% reduce cost each time you charge hero. This will fastly result in very costly angry mobs.

Rest of empty space you can fill whit Soul Reaper rune (it helps a lot whit orb generation) , Barrage rune or swift strike runes so full version can something look like this.

So now you have 5 heroes which all can release strong angry mob for reasonable price of orbs.
You know rule hoe to angry mob travel so now is time to get to the game.

Ideally first 20 waves (including boos) you shout take whit hout using angry mob (charge hero on lvl 6). Shrines will help you do this especially hero shrines (I always have Jack and Wylde shrine). I don’t build much orb shrines because they give around 100 per minute and soul reaper rune + sam aura generate much more than that)

After 20 wave you want to release angry mob when they are at least 2 wave (3 and more wave is better) on same path. Releasing angry mob only for 1 wave (bosses are exceptions) is waste of valuable orbs.

Don’t release to many angry mobs at once (bosses are exceptions). 3 Angry mob release at one can kill all waves on map and still remain live (which mean you waste some of they strength).

Every 20 wave one of Bosses will came.
Boss on wave 20 and wave 40, can be kill without angry mob but it is hard on the rest you will need angry mob.

Bosses are very dangerous because they have a lot of health and high health regeneration and special abilities. You need at least 3 or 4 Mobs to kill them which is a lot.

Worst boss according to me is Bones, because of his defense and skeleton creation. (sometimes you need up to 5 mobs)
Zombie Queen regenerate very fast so you need send 2 or 3 mobs in some time
Amalgram also regenerate very fast and have slow animation of dying so be careful not to release to many mobs 2 or 3 mobs in some time should take care of him.
Redflang is fast but otherwise he is manageable (2 mobs shout take care of him)
Nightshade is kind of interesting because she will faster other creeps so be ready for that otherwise (3 or 4 mobs should finish her)