To save time, you only need to ask the others about the specific person you intend to frame. As for dialogue choices, simply bring up your target's violent qualities or whatever makes them look abnormal. Talking at the dinner table is also unnecessary.

The Stranger
Weapon: Six-Shooter (next to Bill's bed)
Evidence: Payment agreement found in Old Bill's room
Where to Plant: His bag in the main hall

Ernie
Weapon: Rifle (back room)
Evidence: Key found in Annie's room
Where to Plant: In the room before exiting outback (back room)

Zeke
Weapon: Pickaxe (brewery)
Evidence: Mining letter found in the brewery
Where to Plant: Old Bill's room

Josie
Weapon: Lead Pipe (kitchen)
Evidence: Bloody rag found in Pearl's room
Where to Plant: In the kitchen

Pearl
Weapon: Pocket Knife from her purse (scarlet room)
Evidence: Gold pocket watch found in Old Bill's room
Where to Plant: In Pearl's room

Father Augustine
Weapon: Snake from outback (first assess the snake, then come back to the kitchen and choose the basket)
Evidence: Old Bill's bible found on the patio
Where to Plant: Father Augustine's trouser pocket (on the clothesline outback)

Suicide
Weapon: Six-Shooter
Evidence: Opium bottle found in Pearl's room
Where to Plant: Old Bill's room upstairs

You Die
Weapon: Bare Hands
Evidence: Does not matter
Where to Plant: Does not matter (you will get into a struggle and be strangled)

Do not bring up Old Bill's abusiveness towards you. Obviously, this will draw a lot of suspicion from the Sheriff. It is, however, okay to lie to the sheriff and say that you confronted him about his drinking habits.