I play a tankish 2H DPS-er with a support mage/marksman.

I start the warrior with Zombie and Lone Wolf, the mage with Scientist and Lone Wolf.

Zombie/Leech has so much sustain, can heal himself (get rings and boots with bonus movement) by simply walking on ooze or blood (in small steps), can grenade himself with toxic grenades, can be healed by poison arrow (author’s choice), by Magical Poison Dart and Deadly Spores.

Abilities for Warrior:
Bodybuilding, Willpower, Geomancer, Man-at-Arms and Scoundrel
Skills: Walk in Shadows, Melee Power Stance, Summon Spider
8 strength, 7 speed

Summon spider is incredibly strong early, especially since you will be able to summon 2. They scale with player level, not his INT. They have high perception and with Burn my eyes can detect almost anything, if you know where to look. They also bleed ooze, which is awesome for healing your warrior.
Walk in shadows is a must through the entire game, but is awesome at start for some thievery and passing unwanted combats.

Example build for warrior level 7:
https://www.dropbox.com/s/qudcknm65o4fkwq/Warrior%20Level%207.xlsx?dl=0

Abilities for Mage:
Bartering, Witchcraft, Geomancer, Blacksmithing and Crafting
Skills: Summon Spider, Bless, Oath of Desecration
8 intelligence, 7 speed

Example build for mage level 7:
https://www.dropbox.com/s/oubnog7dvnh25sj/Mage%20Level%207.xlsx?dl=0

Level 1-14 my mage goes dual wield with 1 water 1 air wand. Cast rain (warrior should have an immune to frozen and immune to stun ring) and watch the show.
At level 14 I respec mage (remove Lonewolf) and take Jahan for support mage. My main character switches from mage to marksman/mage.

I start the game by exploring. This is my route:
I do the Fire quest (Reputation). I take Broggnar's armor. Get the traits from Cyseal. Get my 1st Bloodstone and the Pyramids. Exit through East Gate. Go to Walter well, and then go to Church graveyard. Use Walk in Shadows past the Graveyard Madman, get Teleport. Say "Grak" to Long Dead Troll and cross the bridge. Go west, take 2nd Bloodstone and Teleport. Go to Luculla. Take Teleport.

You should stop here if you prefer a more challenging game.

Go east to Witch's hut. Take Teleport and solve Icari riddles. Teleport back to Cyseal road. Go north to Silverglen. Talk to Loic (inside the city) to get the Quest, talk to Ahru. Take Teleport. Go north, past the guards to the desert. Speak to Kadraskaz. Take second right and then south till you reach the Goblin village. Talk to totem so you can leave. Enter the Goblin cave east of the totem, because it has a good source of containers (bags). Exit south, take Teleport. Go east to the fortune teller (use pyramids to cross the river to the east). Continue east to Sacred Stone Teleport. Optional: Walk in Shadows straight into the hut and get Tenebrium Tome.

• Pyramids work in combat.
  
• Rapture is a game changer. Saving throw is Willpower, so combine with Drain Willpower or Divine Light.
  
• The name of the game is Bodybuilding (and Willpower). Max to 6 ASAP. That means get Base 4 BB ASAP.
  
• For warrior: Speed > Strength (15) > Constitution > Perception > Int, Dex (later in the game you can get both to 8). At the start of the game, get base STR to 10 and 5 from gear. All other attributes go to speed. At 15 STR your Crippling Blow has CD 1.
  
• Get crafted charisma items for charisma games.
  
• 4 essential items for support (mage): bracers and belt with Blacksmith and Crafting, neck and boots with Bartering.
  
• Try to get gear with immunities: Stunned, Knocked Down, Frozen, Slowed (rings, chest, boots). Weresheep armor will provide immunity to Frozen, Body Building is enough for Knocked Down. I like to put Frozen and Stunned Immunity Rings on my warrior so the mage can have fun with spells.
  
• You no longer need to buy 2H swords from vendor. The crafted ones are awesome.
  
• No good gear can be bought until level 15 (just +1 stats). Just visit vendors and keep buying Metal Scraps, Iron/Steel Bars, Iron Ore and Pickaxes (smelt Pickaxe into Steel Bar and forge 1h Axe, 1000g profit) until then.
  
• Get Leadership 6 on mage ASAP. Base 2 + 3 from gear + 1 from trait.

• Power Stance also increases magic damage (try on wands)
  
• Farsight gives a +50 to hit with ranged AND melee weapons
  
• Mobile Kitchen works as a Furnace. Combine a cooking pot with a fire outside the city so you can place it in your inventory.
  
• Get Bow and bow bracers

• Books spawn at Teller of Secrets at level up
  
• Glass Cannon is so OP
  
• You can farm XP with Icari mushrooms. Elemental damage causes new to spawn
  
• Earth Shield is OP
  
• 6 Bartering and 60 Attitude for even trade

• Agro into enemies with a summon. Optional: cast Water of Life before combat.
  
• Mage casts Oath, Bless (and Wildfire) on Warrior.
  
• In a boss/harder fight, cast Drain Willpower and Slow on the Boss.
  
• Warrior pops Power Stance and hits with Crippling Blow (+ Bully = 50% damage). Auto, Auto, Dead, Next.

Traits are important. Do the quests in Cyseal to get them ASAP. I take:

• Independent (+1 Willpower)
  
• Compassionate (+3% Critical Chance)
  
• Righteous (+1 Leadership)
  
• Blunt (Immune to Charmed)
  
• Bold (+1 Initiative)
  
• Pragmatic (+1 Crafting)
  
• Forgiving (Immune to Cursed)
  
• Egotistical (+1 Bartering)
  
• Spiritual (Immune to Fear)

https://www.reddit.com/r/DivinityOriginalSin/comments/76h0qn/trait_choices_guides/

Warrior:
1) Lone Wolf - Character with no companion but receives: 70% bonus to base vitality, 2 bonus to Turn Action Points and Maximum Action Points, 1 extra Ability Point on level up
2) Leech - Heals you when standing in blood (usually only during your turn)
3) Zombie - Lets you heal from poison but causes damage from regular healing. Essential (get lots of movement, any earth summon, and just walk on ooze in small steps to heal; your mage can also heal you with poison arrow)
4) Bully - 50% damage against opponents that are Slowed, Crippled or Knocked Down; Essential (mass slow, slow,...)
5) Bigger and Better (1 extra Attribute point)

6) Consider Morning Person for Honour mode
7) Swift Footed - Grants +10% movement bonus (optional)
8) Picture of Health - Vitality x 3% x Man-at-Arms level; Good on high Constitution (optional)

Mage (level 1 - 14):
1) Lone Wolf
2) Scientist - Grants players a bonus point in Blacksmithing and one in Crafting
3) Light Stepper - Grants players +2 Perception bonus for detecting traps and secrets (or you can use spider for detection)
4) Far Out Man - Increases the range of spells and scrolls by 2 meters

Mage/Marksman (level 15 - 20):

http://divinityoriginalsin.wiki.fextralife.com/Skills

Warrior (Base):
Two-Handed (5) - Bonus (0); Bonuses on Weapons, Bracers and Belts
Bodybuilding (3) - Bonus (3-4); Bonuses on Chest Armor, Belts, and Leggings (Sarong); 1 from Leadership
Willpower (3) - Bonus (3-5); Bonuses on Weapons, Leggings; 1 from Independant; 1 from Leadership
Geomancer (1) - (*)Bless (later), (*)Summon Spider (at level 1)
Man-At-Arms (4)
Scoundrel (2) - Walk in Shadows, Cloak and Dagger, Fast Track, Become Air
Leadership (1) - Bonus (3-4); Bonuses on Helmets and Weapons; 1 from Righteous
Loremaster (2) - Bonus (3); Bonuses on Amulets and Rings
Charisma (0) - Bonus (4); Bonuses on Amulets, Rings, Belt (For paper-rock-scissors and arguing with mage)
Tenebrium (2)
Rest go into Attributes!

Mage:
Dual Wielding (2)
Wand (2)
Bodybuilding (2)
Willpower (2)
Hydrosophist (4) - Avatar of Frost (1), (*)Rain (1), (*)Regeneration (1), (*)Slow Current (2), (*)Water of Life (2), Ice Shard (3), Cleansing Water (3), Mass Slow (4), Hail Attack (4)
Witchcraft (3) - Malediction (1), (*)Oath Of Desecration (1), (*)Drain Willpower (3), (*)Rapture (2)
Pyrokinetic (2) - Avatar of Fire (2), (*)Burn My Eyes, Wildfire (2), (*)Fire Absorption Shield (3), Fireball (3), (*)Purifying Fire (3)
Geomancer (4) - (*)Bless, (*)Summon Spider, (*)Magical Poison Dart, Summon Poison Slug, Deadly Spores, (*)Earthquake is finally awesome
Aerotheurge (1) - Avatar of Storms (2), (*)Bitter Cold (1), Teleportation (1), Wind of Change (1), Invisibility (2), Tornado (3)
Bartering (3-5) - Bonus (3); Bonuses on Boots and Amulets; 1 from Egotistical
Leadership (3) - Bonus (4); Bonuses on Wand and Head; 1 from Righteous
Blacksmithing (2) - Bonus (3); Bonuses on Bracers and Belts; 1 from Scientist
Crafting (1) - Bonus (4); Bonuses on Bracers and Belts; 1 from Scientist; 1 from Pragmatic

• Most important (money wise), to be purchased on every vendor visit: Iron ore, Iron Bar, Steel Bar; at level 20, each is worth ~1.500 gold.
  
• Iron ore to make Iron Bar = Iron Ore + Furnace; Superior Sword = Iron Bar + Anvill (799 - 1999 @ level 21). You should also buy white swords and smelt them into Bars.
  
• Metal Scraps; Homemade Metal Armor = Metal Scraps + Hammer (2000 - 2500 @ level 21)
  
• Skulls, Bones, Stardust Herb for making magic stuff and scrolls/books.
  
• Tormented Soul adds +2 Dexterity and +2 Strength (+3 /+3 if you are level 22+) to any weapon; Sold by Cylia (Cyseal), Kadraskaz (Luculla)
  
• Ruby and Essences add magic resists on Head, Chest and Legs
  
• Nine Inch Nails
  
• Tooth, Tusk, Thread, Jeweller's Kit Ring, Rope
  
• Pickaxes! - smelt

Purchase & collect:
Sinew, Log, Branch, Knife (Knife at the End of Time, Knife @ Hunter's Edge,...), Iron Bar, Steel Bar, Pickaxe, Metal Scraps, Leather Scraps, Animal Hide, Cloth Scraps, Blank Scrolls

Armor

• Knife + Animal Hide = Leather Scraps
  
• Magic Needle and Thread + Leather Scraps = Leather Armor (1200 - 1800 gold @ level 23)
  
• Magic Needle and Thread + Cloth Scraps = Cloth Armor (+INT) (2000 - 2900 gold @ 23)
  
• Hammer + Metal Scraps = Plate Armor (2100 - 2700 gold @ 23)
  
• Anvil + Scraps = Boots (+Movement)

Weapons

• Anvil + Large Iron Bar = 2H Sword (str bonus, better than axe early)
  
• Anvil + Large Steel Bar = 2H Axe (crit bonus, better than sword late)
  
• Sinew + Sinew = Bowstring
  
• Log + Axe = Branch
  
• Branch + Bowstring = Bow (2000 - 2400 @ 23)
  
• Anvil + Knife = Dagger (600 - 2000 @ 23)
  
• Anvil + Iron Bar = 1H Sword (800 - 2200 @ 23)
  
• Anvil + Steel Bar = 1H Axe (800 - 2200 @ 23)

Enhancements

• Weapon + Tormented Soul = Weapon (+1/2/3 STR, +1/2/3 DEX)
  
• Weapon + Whetstone Wheel = Weapon (boosted damage)
  
• Weapon + Tenebrium Bar = Weapon (boosted with Tenebrium damage)
  
• Crossbow + Bowstring = Crossbow (boosted damage)
  
• (Chest) Anvil removes the Movement penalty from Armor and replaces it with +0.10 Movement; Use scraps to boost armor rating
  
• (Feet) Adding Nine Inch Nails to your Boots adds Immunity to Slipping

Misc

• (CHA) Get 4 +1 Charisma items for annoying Paper/Rock/Scissors games:
  
• Magic Tooth (Tusk) = Pixie Dust + Tooth (Tusk) | Amulet = Thread + Magic Tooth | Ring = Jeweller's Kit Ring + Magic Tooth | Belt = Rope + Magic Tooth
  
• Pixie Dust = Bonedust + Stardust; Stardust = Stardust Herb + Mortar and Pestle; Bonedust = Mortar and Pestle + Bone/Skull
  
• Iron Bar = Iron Ore + Furnace
  
• Same for all schools: Blank Witchcraft Skillbook = Blank Witchcraft Scroll + Blank Witchcraft Scroll
  
• Any Potion + Augmentor = Stronger Version of The Potion
  
• Skull + Pixie Dust = Magical Skull
  
• Magical Skull + Rope = Skull Belt (+1 INT)
  
• Tusk + Pixie Dust = Magical Tusk
  
• Magical Tusk + Rope = Tusk Belt (+1 BB)
  
• Feather Belt (+1 DEX)
  
• Eye Amulet
  
• Feather Amulet
  
• Tusk Amulet

This guy wrote a nice tutorial
https://docs.google.com/document/d/1skVuINeNSoqDYqn7FzufVtXS3sxUK-cp1Zgb73uV6lI/edit

• Anvil + Large Iron Bar = 2H Sword (+STR)
  
• Leather Boots (+move) = Anvil + Leather Scraps
  
• Robe (+INT or +SPD) = Magic Needle and Thread + Cloth Scraps
  
• Boosted Robe = Robe + Leather Scraps
  
• Claw Amulet (+STR) = Thread + Magic Claw
  
• Magical Tusk + Rope = Tusk Belt (+1 Body building)
  
• Magical Skull + Rope = Skull Belt (+1 Inteligence)

• You can farm vendors, they change inventory per hour.
  
• Take Bartering Base 3 on your mage, +3 from items. This should be enough.
  
• You should sell all your stuff to 1 to 2 vendors, preferably with high attitude (100). Fish vendor has attitude 100 after you do the quest, Esmeralda when you finish A Mysterious Murder.
  
• Double up. I'm the guy who killed Drizzt in Baldur's Gate, so, mid game, when I sold enough to a single vendor, I kill him and start selling to another. So, it's wise to sell to secluded people. I sell all crafted swords/axes to Immaculate Teacher at Sacred Stone.
  
• Smelt back all white swords/axes/Pickaxe (I buy all the one hand swords/axes from vendors, a bit overkill). Then craft 1.500 gold swords and sell them (to the vendor you're going to kill)

• The End of Time - Trader's Emporium - Brian
  
• Cyseal North Gate - Selenia, Quartermaster (Ingredients), Aureus, Cylia (Ingredients), Fletcher, Fish (sell only), Esmeralda, Shereth
  
• Silverglen - Kadraskaz (Ingredients), Bjorn, Sebi (Ingredients), Nadia, Mikhail (Ingredients), Elwyn, Ellary (Ingredients), Hiver, Windemere, Hassat
  
• Sacred Stone - Apprentice, Enlightened Teacher (sell only, I sell all crafted swords/axes to him, then I kill him), Attenberah
  
• Hunter's Edge - Stabigg, Gysonn, Hortun (Ingredients)

• If you need to go somewhere and then come back, leave a character there, then use the Pyramids to come back.
  
• Maradino's Ghost - endless XP, just keep killing his summons.
  
• You can trade 3 Ability points for an Attribute.
  
• At level 16 I go kill the Weresheep. There is a trick to go to it without finishing the Wizard quest. Next to the donate thingie, there is a tree you can throw your pyramid to.
  
• Rain to create puddles, Ice Shard to freeze them.
  
• Barrel is an Ingredient (good for sorting).

https://docs.google.com/spreadsheets/d/1-5FyqMqYchmDTh_ldPnNZzrJ0p6sew9LzX1mXpTrfdA/edit?usp=sharing

Achievement Guide
http://divinityoriginalsin.wiki.fextralife.com/Trophy+and+Achievement+Guide

Awesome read: Daggers are better
http://gtm.steamproxy.vip/app/373420/discussions/0/357284767244750359/

For those who want more challenge from the game:

Create folder:
Divinity Original Sin Enhanced Edition\Data\Public\Shared\Stats\Generated\Data

Copy Character.txt into the folder. You can download it here:
https://www.dropbox.com/s/f12a643swl1z75f/Character.txt?dl=0

Modifications to the game are as follows:
new entry "HardcoreNPC"
type "Character"
data "Vitality" "120"
data "ChanceToHitBoost" "20"
data "Movement" "1"
data "Willpower" "1"
data "BodyBuilding" "1"
data "Initiative" "3"
data "APRecovery" "4"

This will add these stats to all NPC on tactician mode.

01 - Cyseal - Thelyron's office
02 - Cyseal - The King Crab tavern - Ransacked room
03 - Cyseal - Silverglen Road
04 - Black cove - Pontius' treasure chest
05 - Cyseal - Braccus' tomb
06 - Hiberheim - Prison - inside an Iron Maiden
07 - Hiberheim - Boreas' Treasure Room
08 - Luculla - Immaculate trial stone
09 - Luculla - Silverglen - Basement of the immaculate church
10 - Luculla - Silverglen - Basement of the immaculate church
11 - Luculla - Totem in the goblin village
12 - Luculla - Maradino's lair - Shard
13 - Luculla - Immaculate Cathedral - Mangoth
14 - Phantom Forest - Knight's Tomb
15 - Phantom Forest - The Temple of Death - In the eye of the stone head
16 - Phantom Forest - Source temple behind a mirrow (dig)

Dusty parchments
1st is next to the Legion kitchen in Cyseal
2nd is at the end of Portal Maze in Luculla
3rd is in the first part of Hiberheim, just south of the Hiberheim - Cave Waypoint
4th is in a chest in a bush east of the Wizard's house (480:89)

Portal Maze: N-S-S-N-E-E
Credit to Mister Magician

Portals will be named like this: R_P_
R stands for room, and there are two rooms: R1 and R2
P stands for portal and there are three in each room, one for North, East and South: PN, PE and PS

Start at the default portal. Go in R1PN -> R2PS -> R1PS -> R2PN -> R1PE -> R2PE

Last chest riddles:
0-2-8-1