You want to win as Blade and get your title. Break free of the madness.

Pick the Ancestral Blade perks in Prepare (left-side column). You want to be as far down as possible, ideally level 35+.
Your Abilities selection does not matter. You won't be using your Ultimate, and you will never swap to your pistol.

Here's the juicy bit: which perks to buy with Moon Orbs.

The gist is, buff Ancestral Blade as much as possible. Grab an Ankh. Get enough health and damage reduction to survive certain hits like exploding zombies. Ignore everything else.

More detail:

You will go ALMOST entirely Red + Purple, with one exception:

Grab one Ankh perk from the Blue cards. The Ankh pulls all enemies except Sentinels and bosses into a clump. That's really helpful for your team, especially when facing waves of Exploding zombies. You don't need to stack Ankh perks because it's a % chance to spawn on hit, and your attack rate will be very high. You can only have a limited number of active Ankhs at a time, and they last a set duration.

Reds:
IGNORE LIFESTEAL CONVERSION. You will be in Bloodline Awakening 100% of the time. You already convert a % of damage dealt. Lifesteal conversion % does nothing for you. Adding +damage already means +lifesteal.
Always buy red +damage.
Always buy red +attack speed.
Always buy red +range until you can reach distant mobs. You eventually stop needing more range.
Never buy any buffs for the ult (Thousand blah blah blah = ignore).

Purples:
Buy some +450hp until you have at least 7k hp. Ignore lower +hp as it's an inefficient use of Orbs, and don't over-invest in hp. 15k incoming damage is a one-shot whether you have 4k hp or 14k hp.
Always buy damage reduction. It stacks very efficiently.
Lightning chain is optional. You can get higher DPS by only buying +dmg and +atk speed for Ancestral Blade.
Freeze effect is optional. It can be helpful to manage hordes for your team. Don't over-invest in it if you do get it.
+Damage purples are optional, unless you are also buying lightning. 1pt for purple is +2.5% damage, 10pts for red is +140% damage. Red is way more efficient spend. You only need the one damage source, Ancestral Blade.

Blue:
Grab one Ankh card and ignore the rest.