Survive 10 minutes without moving
Video proof (Also on youtube if you prefer to watch on YT:
ttps:/www.youtube.com/watch?v=sfRQVwt0iMs

The build is simple, you can use anything with a strong start like Megachad or Athena.
Athena being the easier one but harder to unlock.

First pick - Try to get a second weapon ASAP so you can do some raw DPS and not die to regular mobs.
Second pick - Unless you get pick up range, quantity, pick a third weapon

Aegis - Aegis tanks one shot and also reflects damage. Recharges periodically, scales with QUANTITY tome.
Axe - Strong knockback, also creates directional bias, you can create a weak side to let the mobs push you.
Tornado - Strong knockback, not directional like the axe however
Dexcutioner - Extremely strong close range
Other projectiles - Dice, blades, bananas are ok as filler weapons
Aura - Great but make sure you have pickup range to back this up.

Pick up range - Useless in normal mode but very essential in AFK challenge
Lifesteal - This addresses the problem of not surviving long enough.
HP - With enough HP you can bruteforce everything. Also plenty of chance for you to recover.
Quantity - The reason why you take quantity over damage is 2 blades = 200% damage. Not even gold damage tome gives you 200%. Compounded by the fact that you are only here for 10 minutes, you do not have time to scale a damage tome.
Pushback tome - If you got good pickup range but lacks a bit in damage, this is a viable option

Campfire - Heals you while you stand
Idle Juice - Increase attack while you stand
Moldy Cheese - The meta boss wiper

Poison bottle - Too slow
Revolver - Insufficient crowd control, Wipes out enemy too far, you cannot pick up the exp.
Sniper - Wipes out enemy too far, you cannot pick up the exp. Can be manually aimed but still too much collacteral damage.

Damage tome - You DO NOT LACK DAMAGE here. You need to LAST the 10 mins. Let quantity make up for the damage instead.
Movement speed tome - You are not moving.
Luck/exp tome - You are only doing 10 minutes, the impact you will see is minimal, EXP can be ok if picked early
Spike tome - You do enough damage, spike is not necessary

• You can still rotate while being locked for the challenge, certain attacks, ie firewalk, swords, axe and so you will have directional attacks, use it to your advantage
  
• Build for the challenge, you are not fighting t3 boss here.
  
• If you have the toggler you CAN remove most tomes and weapons you don't want from the loot pool to increase your chance of obtaining favorable items. To do this, go to where you unlock them, there's a yellow checkmark on top left, click it and disable the item from being in your loot pool.