Full credit for this goes to Coffee コーヒー on the discord. I assume it was a group effort but Im not gonna spend hours trawling the discord for full credit. Spoiler warning if you wanna figure these out yourself.

So, one thing the game doesn't tell you is that multiple features that, in my opinion, should have been menu settings are locked behind a system called Praying. It's relatively straightforwards and some of them are actually rewards for figuring out the minor puzzle involved, but I thought some people might want to know, like me, as I've been tearing my hair out.

To activate a blessing (most of the time) you need to have the relevant curio (the sigil, you get it from the arena puzzle associated with each), activate the relevant blessing by interacting with the item in the town that's associated (other guides have pics), and then find the relevant shrine.

Astrolabe sends you to tower floor 37 from any dungeon and gives you 3 packs (1 gold 2 tower)

Crystal gives you an extra gemstone on return.

Glass (which only appears as a way to redo boss fights), hits the boss for 10dmg but also hexes you.

Hearth sets the current dungeon miasma to 0 (Extremely useful if you wait to do your quests until postgame, like most players appear to)

Jar converts some number of shards to some number of gems

Mallet, assuming you have exactly 0 gems, turns the entire room into gold chests

Quill turns you into the last other possible player character you talked to (possibly requires you to reload the save immediately). This is the only way to change your character without starting from scratch.

Rope lets you fish twice...hooray

Stone gives you copies of the cards Prayer, Dig Deep, and Mourning

Sword gives you Immune 1 at the start of the fight

Tome gives you a permanent copy of a card you don't have, but only if you have no cards in your graveyard and you can't be in Misty Grove. There is a warning on the discord that this can bug the game by letting you get copies of quest cards you should only be able to get one of, but, I don't think that's a big deal. Does nothing if you have them all.

Torch has not been discovered as of when I'm writing this guide (Coffee was still looking on 1/9/25, a dev commented on 1/31/25 that it's very cool). If someone finds it and comments here, I'll update the guide.

And that's the praying system. People kept alluding to it in discussions but no one ever explained, so I joined the discord just to grab it. Hope this saves some other people some frustration. Now, back to losing my mind trying to 100% the game.