Open the Engine.ini file from : "C:\Users\YourUserNameHere\AppData\Local\Stalker2\Saved\Config\Windows"
And add these lines (If the Engine.ini file doesn't exist, simply create it) :

[/script/engine.renderersettings]
r.TemporalAA.HistoryScreenpercentage=200
r.TemporalAA.Mobile.UseCompute=1
r.TemporalAA.R11G11B10History=1
r.TemporalAA.UseMobileConfig=1
r.TemporalAAPauseCorrect=1
r.TemporalAACatmullRom=0
r.TemporalAA.Algorithm=0
r.TemporalAA.Quality=2
r.TSR.ShadingRejection.ExposureOffset=3.0
r.TSR.Resurrection.PersistentFrameCount=2
r.TSR.ShadingRejection.TileOverscan=3
r.TSR.ShadingRejection.SampleCount=0
r.TSR.RejectionAntiAliasingQuality=2
r.TSR.ShadingRejection.Flickering=1
r.TSR.History.ScreenPercentage=200
r.TSR.History.GrandReprojection=1
r.TSR.Velocity.Extrapolation=1
r.TSR.History.UpdateQuality=3
r.TSR.History.R11G11B10=1
r.TSR.Resurrection=1
fort.TSR.Enable=1
r.TSR.16BitVALU=0
r.BasePassForceOutputsVelocity=1
r.VelocityOutputPass=1
r.FXAA.Quality=5

These include TAA settings as well if you prefer to use that, although results might not be as good as TSR, which is superior in most aspects.

I suggest using TSR on Ultra Quality and at 100% scale, do note that these settings are heavier than the base game ones and thus will reduce performance slightly, although it looks significantly better.

Overall these settings greatly improve image clarity, reduce ghosting and better retain fine details even in movement.

Credits to TheHybred for his work, simply putting this guide here for visibility.
https://next.nexusmods.com/profile/TheHybred?gameId=6944

Screenshots below are taken at 1080p native with this guide's settings.