Hello all, this is a guide to augmentations & mutations. This guide is to tell you what they do and how well they do them. However, this guide is rather shallow as I have not experienced every single event and am only piecing together evidence of several starter characters. If you have more information to add to this guide, please leave a comment on this guide and I will add you. If you prefer to contact me via discord my @ is: _jagr (please @ me via the cyberpunkdreams discord, I do not accept random friend requests. my nickname on the discord is Beelzebub). Please keep in mind that roleplay serves a large part in this game, min/maxing may leave you bored. The ??? after events/mutations means I have not yet found the outcome and welcome anyone with information. The ; separates events.
Stat acronyms:
Charisma-Cha
Cunning-Cun
Discipline-Dis
Perception-Per
Reflexes-Ref
Resilience-Res
Stamina-Sta
Strength-Str

Sex stats:
Female: Res +2, Cha +2, Ref +1, Str -1
Male: Cha -1, Dis +1, Sta +2, Str +2

Augmentations: Here is a list of all starter augmentations (minus neural interface). Please note that raised skills only raise when one skill is higher than the other two (if all three are the same level, level will not be raised).

Core System: ???. Skills: Medicine, ???, ???. Events: The Shakes: Shakes-, Hardship-; Hidden Reserves: Boosted/Dis+1, Boosted/Ref+1, Boosted/Res+1 (May be random boosts). Credit to LioTheManlyBadassHero for info.

Empathy enhancer: Cha+2, Cun+1. Skills: Empathy, Persuasion, Flirting. Events: Work on your relationships[Max 10 Connected, Max 10 Good Contact]: Well Connected+1; Work your charisma: Boosted/Cha+2

Enhanced retinas: Per+2, Ref+1. Skills: Throwing, Observation, Long Range. Events: See what you can see: Patterns+2; Master your perceptions [Requires Boosted Per+Ref]: Boosted/Per+1, Boosted/Ref+2

Fingertip Razorblades: Ref+2, Melee Weapon. Skills: Hand to hand, Sleight of Hand, Silent Kill. Events: Look after your blades[Requires Cleaning Kit]: Satisfaction+1, Boosted/Ref+2

Internal armour: Res+2. Skills: Mechanic, Hand to hand, Explosives. Events: Injured? (Luck Check Fail): Injury+; Injured? (Luck Check Succeed): Injury-

Neural Interface: ???

Pain Controller: Sta+1, Dis+1. Skills: Intimidation , Knives, and Unarmed. Events: Boosted/Disc +2; Control Pain: Pain-; Shrug it off: Hardship-

Systemic regulator: Cun+2, Str+1. Skills: Riding, Silent Kill, First Aid. Events: Increase your need: Need+; Deal with it: Psycosis-; Reduce your needs: Need-

Support System: Sta+2, Ref+1. Skills: Sneak, Heavy Weapons, Close Range. Events: Hardship-, Buzz+1.

Wrist Slugs: Str+2, Melee Weapon. Skills: Unarmed, Intimidation, Throwing; Events: Focus on Fighting: Hand to Hand+, Unarmed+; Building Muscle: ???. Credit to LioTheManlyBadassHero for info.

Acute Sense of Smell: Per+1. Events: Let it Breathe (Per Fail): Hardship+, Irritation+1; Let it Breathe (Per Success): ???

Cannibal [Disables Vampire]: Sta+1. Events: Satiated(1 day without flesh): Satisfaction+2; ???

Deep Reserves [Requires 1 Other Mutation]: Sta+1. Events: Boost yourself(Luck10%/Fail): Stam/hit+2; Boost yourself(Luck10%/Success): ???; Hungry?: Hunger-; Need energy?: Carpe Diem+

Electric skin: Electric Skin Weapon. Events: ???

Endocrine control: Dis+1. Events: ???

Extra Finger Joints [Requires 1 Other Mutation]: Events: Skills: Raise Electronics, Mechanics, Silent Kill, Sleight of Hand, Satisfaction+1; Flex [Min 1 Hardship Requirement]: Boosted/Ref+2, Hardship-, Satisfaction+1

Fast healing: Res +1. Events: Nothing major: Hunger+, Injury-, Lethargy+1

Feline Chimerism: Ref+1. Events: Tired: Alertness-1, Relaxation+1; Purr (Living Space Required): Hardship-, Satisfaction-2, Relaxation+2; Amped up: Boosted/Per+3, Distraction+1

Immune [Requires 1 Other Mutation]: Protection from Toxins, mutated immune system. Events: Your immunity: Boosted/Res+1, Boosted/Sta+2

Immune From Pain: Dis +1. Events: A different kind of life(Luck50% Check Fail): Psychosis-, Hardship-; A different kind of life(Luck50% Check Success): Satisfaction+2, Enthusiasm+1; Cautious? (Cautious Check Fail): Injury+, Hardship+, Caution-1; Cautious? (Cautious Check Success): ???; Battered? (Luck80%/Res Check Fail): Injury+, Hardship+, Cautious+1; Battered? (Luck80%/Res Check Success): ???; Your Skills (Cun Check Fail): ???; Your Skills (Cun Check Success): Raise First Aid, Physical Labor, Medicine, Long Range, Intimidation (NOTE: This event may just raise skills that your char already highest);

Intense Memory [Requires 1 Other Mutation]: Cun+1. Events: See what you can remember: Patterns+3 or +4; Work on your mind: Training Your Mind+1, Analytical Thinking; Your imagination: ???

Lupine Chimerism [Disables Low Body Temperature]: Stam +1, Arctic Temperament Quirk. Events: Pack alpha: Skill Increase to: Leadership, Intimidation, and Survival; On the streets: Warming up+2, Psychosis-, Thrill+1, Hardship-, Psychosis-

Poison Tipped Tail [Requires 2 Positive Mutations & 1 Negative]: Ref+1, Tail is Lethal and/or sexual. Events: Practice (Ref/HandtoHand Check Success): Carpie Diem-1, Raise hand to hand, sleight of hand, knives, Boosted/Ref+2, Satisfaction+1; Martial Arts (Ref/Martial Arts Check Fail): ???; Martial arts (Ref/Martial Arts Check Success): ???; Your moves: Raise Intimidation,Sleight of hand, torture, Psychosis-; Admire it: Thrill+1, Buzz+1, Enthusiasm+1, Hardship-; Milk it: ???

Reactive biochemistry: Lowers hangovers & comedowns. Events: ???

Sensitive Hearing [Requires 1 Other Mutation]: Per+1. Events: What can you hear? (Per/Observation Check Fail): Observation+

Separated Hemispheres: Cha+1. Events: Social animal: Well Connected+3, Good Contact+2, Empathy+, Business+; Sleep[Requires Max 4 Alert]: Alert+; Wired Up: Irritation+1, Aggression+

Sexless [Requires 2 Positive Mutations & 1 Negative]: ??? Events: ???

Simian Chimerism (Chimp): Str+1. Events: Amped up: Boosted/Ref+2

Simian Chimerism (Gorilla): Str+2, Ref-1, Getting Bigger+1, Wall of Muscle/Quirk+. Events: Tough: Boosted/Res+2, Injury-; Collected: Boosted/Dis+2, Irritation-1, Frustration-1

Sixth Sense: Cun +1. Events: People after you?: Caution+1, Hostile Forces+1; Open your mind (Dis/LateralThinking Check Fail): ???; Open your mind(Dis/LateralThinking Check Succeess): ???; The things you’ve learned: Raise Observation, Sneak, Urbex, Urban Survival

Third breast [Requires Female] [Requires 1 Other Mutation]: Quirk/Perfect Breasts. Events: Look[Requires Place to Stay]: Satisfaction+1, Flirtation+, Persuasion+

Unnaturally Flexible [Disables Osteophyte]: Ref+1. Events: Strong enough? (Str Check Fail): ???; Strong enough? (Str Check Success): Satisfaction+1, Boosted/Res+1; Stretch: Boosted/Ref+1, Boosted/Ref+1, Boosted/Sta+1, Satisfaction+1, Need+1, High/Endorphins+1, Warming Up+6, Overstretching?+1; Your skills: Sneak+, Urbex+, Hand to Hand+, Sleight of Hand+; Really get into yourself: Relaxation+1, Boosted/Res+1, Boosted/Sta+1, Need+1, Propesnity/Endorphins+, Hunger+, WarmingUp+6, Satisfaction+2, Carpe Diem-2;

Vampire [Disables Cannibal][Requires 2 Positive Mutations & 1 Negative]: Str+1, Ref+1. Events: Adds Vampire Content; Blood Intake Upkeep; Blood-music [Access Code], Supply: Patterns-4, Fresh Blood+2, Blood Supply+1

Always Hungry: Sta-1. Events: Denying Hunger (Dis Fail): Increase Hunger Rate, Increase Hardship; Denying hunger (Dis Success): Capre Diem+1, Analytical Thinking+; Live With It: Distraction +1, Hit/Charisma, +Hunger OR Boosted Str+1, Boosted Cha+1

Deranged Mouthparts: Events: Not too bad: Hit/Cha+1, Discomfort+1, Hardship+; Broken Jaw; ???

Horse ♥♥♥♥ (Hate it) [Requires Male]: Events: Ignore it (Dis Check Fail): ???; Ignore it (Dis Check Success): Distraction+1, Psychosis+; Stirring (Dis Check Fail): ???; Stirring (Dis Check Success): Carpe Diem+1, Discomfort+1

Horse ♥♥♥♥ (Love it) [Requires Male]: Events: ???

Low body temperature [Disables Lupine Chimerism]: Cha-1, Tropical Temperement Quirk. Events: Your people: Hit/Cha-2, Harsh Times+2, Persuasion-; Suffer: Hardship+, Hunger+, Hit/Char-1

Metalphile: Events: Pins: Injury+, Psychosis+, Hit/Ref+2, Need for Metal-1; Do your Breasts (Requires place to stay): Injury+, Psychosis+, Hit/Ref+1, Need for Metal-2

Osteophyte [Disables Unnaturally Flexible]: Ref-1, Medical Tools +1, Raise Medicine to 6; Events: Adds armor; Aches and pains (Max Day 3): Hardship+, Injury+;

Poor Concentration: Cun-1. Events: Sleepy: Alert-, Good Contact-, Harsh Times+, Hit/Cha-2; Wandering: Analytical Thinking-; Ideas: Skewed Idea+1, Rare Insight-1, Lateral Thinking+

Unreliable Flesh: Dis-1. Events: Itching (Dis Check Fail): Injury+, Psychosis+, Carpe Diem-2, Frustration+1; Itching (Dis Check Success): ???

Unusual Feet: Sta+1. Events: ???

Weak Skin: Res-1. Events: Injury+, Pain+; ???

This is my personal tier list for all the augmentations and mutations (I will expand upon these at a later date). Keep in mind I have not fully tested all of the mutations:

S Explanation:
Metalphile provides some negative events, but the debuffs provided is pretty negligible.
Unusual Feet is the only negative mutation that provides an increase to a stat (Sta). The negative events associated with this mutation are also pretty negligible.
Poison Tipped Tail provides a lot of skill buffs and a unique tool for combat and/or sexual encounters!

F Explanation:
Weak Skin makes you get injured way more, and random events include injuries that take real life days to recover from!
Poor Concentration provides incredibly annoying random events that cripple your charisma and more importantly your alertness, further limiting what you can do that in game day. Separated Hemispheres can help offset the alertness debuff.
Low Body Temperature provides really annoying debuffs that trigger often. Note that I have only tried this trait out in the Winter with the base game clothing, this mutation is likely not bad during hotter seasons or with much more clothes on.