I recommend you have berserker, bat budget, and mad scientist unlocked. This guide is designed for mega brutal. SAVE OFTEN!

Start in Greenland or Iceland.

Purchase blood rage 1 and 2.

Kill all of Greenland/Iceland to buy blood rage 3 and 4 as well therianthropy and dark ritual. Fly to Europe.

Wait for Templar to spawn, then save up to purchase blood rage 4. Kill all Templar. Upgrade flight speed at the same time to save time.

This is where the waiting game begins. Do not upgrade any infection upgrades and only use blood rage. Purchase lairs to help heal the vampire in countries that don't have any population left. I recommend starting in South America. Kill everyone on earth to win.

For added challenge try to build a lair in every country.