Slaughter Horse 2 provides you with lots of options and tools for completing your objective, and is not afraid to offer tips and advice, but is also very much content to let you make your own mistakes. Some of the actions you can take are more thematic than actually effective, or how they work best may not be clear at first. While I would say there are still elements of luck to actually winning a game, knowing how to approach each situation the game throws at you is helpful for actually making the town bow before you. I have won several games, and below are my findings for the various game mechanics and how to use them to deal with the ponies who call your town home.

As far as using the guide, I would say it is very much set up so that you can read up on a few key things you have questions about, or read the entire thing if you are newer to the game. I have tried to minimize overlap with the wiki, focusing more on how to use the resources, not as much about how they work.

Number of Ponies/Days until Thaw
The number of ponies is pretty much up to you, and is most dependent on which achievements you are going for, if any. It is easier to kill ponies in larger towns because more of them are townies, but I would say it is easier to get used to the various roles' mechanics on a smaller town size because they represent a larger percentage of the population. You want around 1.5 days per pony (20-30, 30-45, 40-60).
Challenges
Only recommended for players who have beat the game several times already. These can be mixed and matched. Good luck if you attempt to win with all challenges active.
Optional Settings
Customization makes the game more enjoyable, but doesn’t affect game mechanics.

Suspicion (Sus)
It is extremely hard to get rid of sus, so you want to do everything in your power to avoid becoming suspicious. It is easier to avoid suspicion if you stay as sane as possible. It may be too late if you get into the yellow.
The following can increase your Suspicion (several are preventable, *** indicates several points of Sus):

• Letting your sanity get too low
  
• Failing interviews by the Deputy, Sheriff, Alicorn, or Magician
  
• The Reporter finding remains in your house
  
• Being seen by the Lookout/Alicorn while attempting a murder (indirectly)
  
• Selecting the Gossip or Interrogate option at your shop
  
• Getting blackmailed
  
• Failing to kill the Disciple before they turn on you
  
• Attempting to kill an on-guard Veteran
  
• Drawing the Death tarot card later in the game
  
• Participating in certain events
  
• Getting Jinxed by the Mule (Maximum Sus)
  
• Including your name in a Death Letter

You can remove Sus by:

• Clicking the correct holy prayer(s) at church
  
• Drawing the Ace of Knives tarot card
  
• Participating in certain events
  
• Clicking a silver circle when being investigated (RNG)

Sanity
You can lose sanity for the reasons listed below. You want to minimize dings to sanity and keep it high, as high sanity helps with a variety of mechanics.

• Attempting to murder a pony and failing for any reason
  
• Allowing your bloodlust to stay imperative
  
• Clicking on a holy prayer at church
  
• Drawing the Moon tarot card
  
• Participating in certain events

You can gain sanity back by:

• Killing a pony
  
• Drawing the Sun tarot card while the Lookout is dead
  
• Participating in certain events

Bloodlust
This indicates the number of days since you successfully killed a pony (Death by Chocolate cake counts). You NEVER want to let it get imperative, as a variety of things can prevent you from killing. Act like it is imperative at four, and try to kill when it’s at three. While not preferable, you may have to kill a townie to ensure it stays down. Do NOT invite a pony if your bloodlust is at or near imperative.
Luck
Your luck based on your tarot card draw. Mainly affects certain events.
Friendship
This indicates how well you’ve made friends with the ponies of the town, and you definitely want to keep this up. Friendliness helps the town trust you, and can help you avoid being lynched.
Remains
The amount of pony flesh you have in your basement. You can get flesh by killing a pony, or by sending your pet to the morgue. Flesh can be used to bake cakes, but should otherwise be disposed of daily.
Ingredients
Shows which ingredients you have, although you have to check the Recipe Book to know what you can bake.
Finding Ingredients
I am sure that you have a chance of finding ingredients from the following actions:

• Killing a pony in their house
  
• Attempting to kill a pony in their house
  
• Having your pet investigate a house
  
• Getting the Special Delivery event

Lynch Mobs
As the town gets angrier and angrier, they work towards building a gallows, and the town will attempt to start hanging ponies once it is complete. The mayor can normally prevent lynchings, or at least reduce their frequency, so it is suggested to leave the mayor alive until you’re sure you are in a good spot to let the ponies lynch each other to death. Some other roles can prevent lynchings if the town is not out for blood, but it is too late once the town is out for blood (seen in the newspaper). This will always be part of the game if it goes on long enough for you to win, which is why keeping your Friendship and Sanity high, and your Sus low, are so critical.
At Home vs Killable
Knowing that a pony will be home does not mean you will be able to kill them. Especially with roles that usually work, they may be home because they expect a visit from another role that usually works. Messages of the Naturist or Veteran being home should be ignored, but other roles can be followed up on.
Sus and Sanity of Townsponies
Townsponies also suffer from losses of Sanity and added Suspicion for certain reasons. These can be seen from the roster; the left vertical bar is Sus, and the right vertical bar is Sanity. When ponies are lynched, the votes are normally cast for the pony with the highest Sus or the lowest Sanity (most ponies are lynched based on Sanity alone). Several of the tools at your disposal, like Gaslighting, Death Letters, and Cakes focus on these mechanics, which is why it is important to use them later in the game when lynchings are frequent. If you can, avoid killing ponies who have a lot of Sus, as they are very likely to get lynched. Using the example below, the town would likely lynch Ivory Hope for having lower Sanity.

These are available at all times, and you will want to be referencing these to determine who to kill when, and how.
Hit List
Useful for seeing which roles are alive and generally active, or for ensuring you have the cutie marks of all dead ponies (14 in list plus the Changeling Spy for 15 total). Sometimes you get lucky and notice that a normally active role is not active, making for an easy kill.
Roster
Details about each pony. Most information found in game is compiled here, but certain information, such as “X role is a stallion” or “X role is a pegasus” are NOT saved here (but are saved in your Notes).
Notes
This logs certain key information from each day such as your tarot card, what your disciple and pet told you, and the day. Some key information (especially your nightly actions) are left out. You can add your own notes at any time. Cheats can be entered here (although this disables earning knives and achievements).
Town Map
Shows you the map of the town. There is some key information that can be seen at a glance from the town map. Most of these rely on you to gather intel from your Disciple or pet. You may need to go into free view to see it, but you can track the progress of the gallows by looking at the center of town.

• White house number = No information
  
• Blue house number = Name known, but not role
  
• Green house number = Ponies on your hit list (besides Disciple)
  
• Yellow house number = Townie (no role or hidden role)
  
• Red house number = Pony is dead
  
• Red X near house number = You have attempted to murder at this address and were unsuccessful
  
• Green X near house number = Your pet has visited this house.
  
• Magical force field around a house = Magician's house
  
• Rubble instead of a house = house of dead changeling

Recipe Book
This shows how to make each of the 6 cakes (recipes are randomized). You can bake a cake if both non-flesh ingredients are in blue, and cakes you have made are crossed out.

Early Game
You get several free kills early in the game, and managing to kill one or more crucial roles is very helpful. The longer you can delay a full investigation, the easier the rest of the game should be. The more information you can gather during this phase, the better. All roles can be killed freely in this phase, except the Naturist, Deputy (after first kill), and Preacher (until Changeling has died). Killing the Lookout or Magician during this phase is very helpful. I have definitely won games both by playing the first few days slow, and also by blindly killing as many ponies as possible before the Investigation.
Full Investigation (Mid Game)
Killing the Noble, Mayor, Deputy, Detective, or Sheriff will trigger a full investigation, which causes several roles to become active, and it means you will be subject to investigations that can raise your Suspicion. You usually have to be more careful with who you choose to kill, and may have to forego killing on account of the Lookout. You may start to be able to bake cakes, and can do so between trying to kill roles strategically. It is during this phase that you need to find and attempt to kill the Magician, Disciple, and Veteran so that none of them can screw you over later in the game. If you can, try to trigger the investigation by killing an investigative role, as the Mayor and Noble are easier to kill after the investigation starts comparatively.
Late Game (Regular Lynch Mobs
It reaches a point where lynchings happen almost every day, and your main priority is to keep your Sanity high and your Suspicion low, as the town is out for blood. At some point, you should know the role and address of all ponies in the town, and this will allow you to kill only as needed to kill your targets or curb your Bloodlust. You should save most of your cakes, all your Death Letters, and potentially your Invitations for this phase, as it is when the first two are most effective. If you run out of Letters and know all the information, you should just be checking ponies that tend to work to catch a day when they are home.
Balancing Kills and Intel
It takes time to collect information on the ponies of the town, so whenever it is feasible, it is best to kill blindly to minimize the amount of research you need to do to know the roles and addresses of all other ponies. Killing a key target when the timing and opportunity are correct will always be preferred, but killing blindly is rather effective as long as you don't hit the Veteran. If you are in the mid to late game and don't know where the Veteran is, stick to safe targets, killing a known Townie if no other options are available. Once the Veteran is known, you can go right back to killing blindly.
Partial Information
While a lot of partial information can be near useless when most of the town is alive, it can be more useful when the population is dwindling (and you can even scroll back through your notes to find bits). One partial piece that is almost always useful is that a pony is working, as this means that the pony is not only a council member, but also a council member that is currently active. This is even more useful in larger towns. On a similar note, it is always worth investigating addresses you find unoccupied.

Day Screen
This is always available, and most of the information is useful. It is useful to keep an eye on the mood of the town and how the town feels towards you. You will want to lay low and be more careful when the town is more suspicious of you. This will show also you which roles are active and for what reason. I am unsure if paying close attention to this can allow you to kill certain roles on their day off.
Reading the Newspaper
Available when the Reporter is alive. This is mostly for flavor, but it can be used to find out who the Disciple is. Pay attention to see if the Disciple says they're going to be visited by the Preacher. If they are visited by the Preacher, their name will be in the newspaper the next day under the section about the Preacher. You can similarly find out which pony lives at an address if the Preacher was with your intended victim the night before.
Tarot Card
The tarot cards are covered in detail in this guide. The main two cards to watch out for are The Magician and The Princess, as these should allow you to kill an investigative role or the Prince/Princess if given an opportunity (respectively). It's worth paying attention to Death and The Tower as well. If you're not sure which card you drew at Night Phase, check your notes.
Disciple Notes
The Disciple can provide a variety of information about ponies in town, including key information such as when certain ponies are home or at work. These are NOT saved in your notes if the information cannot be directly applied to the roster page, so you may want to physically or mentally write them down if you're really trying. This information can help you select a target, or know where to avoid.

Aside from collecting cutie marks and sending cakes or letters, your pet should be gathering info most of the time. I tend to alternate Investigate House and Investigate Pony to try to make sure I’m getting to know both the role and address of ponies consistently, as knowing just one or the other is not helpful for most of the game’s mechanics surrounding methods of killing.
Death Letter
You want to save these until the town has started lynching ponies, as a single letter can encourage the town to lynch the recipient. Good for roles that are hard to kill directly. As far as writing Death Letters, the game is pretty good at detecting what would normally be considered threatening. It seems to be helpful to use words like "kill" "die" "death" "blood" and "murder." You can also mention their role or something related to it, and use most or all of the available space. I personally like using words like "pathetic" or "useless" or "inconsequential," or even "Night Mare" somewhere in there for flavor.
Investigate House
Discover who lives at an address; or, if known, find out if they will be home or working. Default option if the roles of all ponies with known full addresses are known.
Investigate Pony
Discover the role of a pony and additional info; or, if role is known, find out if they will be home or working tonight. Default option if a pony’s full address is known but not their role, or if some intel narrows a key role down to just a couple of ponies. Also the default if all ponies have known addresses and roles.
Plant Remains
This is situational, not to be done randomly. Any investigative role can find planted remains, so if you know one of the investigative roles will be visiting a certain pony (with known address) or is visiting a specific address (other information unnecessary), then you can plant evidence there, and this will increase the Sus of that pony.
Deliver Cake
Be sure about who you are sending each cake, ESPECIALLY Death by Chocolate, as it will trigger a cake ban. Generally a later-game mechanic.
Raid Morgue
Your pet will always grab a set of remains, and has about a 50% chance of grabbing the cutie mark of an important pony as well (if applicable). Can be useful just to grab remains for baking, if you want to bake and lack remains.
No Action
Nearly useless, as there is almost always something useful your pet can do.
Praising or Scolding your Pet
I don't think this makes any difference mechanically, but I suggest praising your pet, if anything.

You can interact with ponies who come to your shop each day. The better your Sus, Sanity, and Friendship stats are, the more consistently you will have four ponies in the shop. You will always have at least one visitor, regardless of your reputation, but a bad reputation limits your customers and options.
Chat
Chat has a chance to raise friendship, and always gets you minor information. This can be used earlier in the game, although I still tend to prefer Frienship.
Gossip
Better information at the risk of reducing sanity or gaining sus. Generally not advisable.
Interrogate
Best information at the risk of adding suspicion. Only advisable in the early to mid game when the Star tarot card is active.
Send Invitation
This has to be the most inconsistent and/or difficult to use mechanic in the game. For a successful invitation, you have to invite a pony who is at least an acquaintance with you, and who is not working that night. This has a better chance of working the higher your friendship level with the pony. It is most consistent to try to invite Townies, but certain important roles can sometimes be successful (I know I’ve gotten the Reporter, Deputy, and Preacher). Ponies can even choose to decline for seemingly no reason, and will always decline if working. Do not rely on this mechanic; if anything, try to use it and appreciate it when it does work, but don't send the letters on a whim.
Gaslight
Completely safe when available, but generally only useful in the late game when lynchings are more frequent. The default option when the number of ponies left is around a quarter of the population or less.
Friendship
Friendship really is magic, and it is truly the default option most of the time. Having at least decent friendship with the town offers many benefits, and this is one of the best ways to keep the bar up. It is worth noting that the investigative roles, and even guarded roles like the Magician and Veteran, may not warm up to you much, if at all. Because of this, it is best to focus on Townies and the friendlier targets like the Visitor, Reporter, Mayor, and Preacher (if roles are known) You can actually take a refusal of friendship as a sign you should have your pet check out the pony's role.

Assuming you aren’t immediately blocked by an investigative role, Preacher, or Guard, you can do something. I find it helps to check your Bloodlust and see if you can bake a cake. Unless you are baking a cake, you ALWAYS want to destroy your remains. Most players are trying to complete the cloak, so make sure to check that you have the cutie marks of all the roles from the Hit List who are dead (plus the Changeling). Then, see if you can commit a murder.
Commit Murder
In the early game, you are going to want to kill blindly for the first few, unless you have already discovered the address and role of a role worth killing early (Lookout, Magician, etc). Later in the game, try to kill roles on your hit list if possible and advisable. You have to be a bit more careful once a full investigation is in effect, and ESPECIALLY if you don’t know where the Veteran is later in the game. Attempting to kill the Veteran later in the game when you don’t know they’re standing down is usually a game over. Later in the game, you may not feasibly be able to get away with a kill, and may not need to to help your Bloodlust. Try not to target a house with a red X unless you know the role and know you can kill them this time around. If being killed directly, some roles MUST be killed at the right time, or else you risk your sanity or suspicion.
Torture Victim
You want to do this right away if the Reporter is alive, and ESPECIALLY if you draw Death or The Tower. Otherwise, you can choose to do it on a later day. They will die of neglect after a few days, but letting them die this way will not reset your Bloodlust.
Bake Cake
Good to do as soon as you can bake a cake you think will be useful, but not if your Bloodlust is near imperative. Note: you cannot go back if you put any ingredients in the pot, so don’t add any unless you intend to and are able to bake a cake.
Destroy Remains
This should be done anytime you have remains unless you are using them to bake a cake that night, regardless of if the Reporter is alive. It is a good habit to get into.
Examine Cloak
Mainly useful if you are actually trying to complete the cloak (which gets you a new knife).
No Action
While you should kill if it is feasible, you want to try and be sure you can kill successfully (to avoid any Suspicion or dings to Sanity). Pick this if you’re not sure you can commit a murder successfully. You will probably pick this option at least a few times per game.

Below I’ve included when and how each role should be killed, and what you generally need to watch out for. Many of these can be killed with patience and tact, or a bit of luck, but you also have the option of trying to get them lynched by arousing suspicion and dislike through Death Letters, Gaslighting, and certain cakes. The Magician is your #1 target, with your Disciple a close second, but beware the Veteran and the Alicorn.
Magician
Extremely dangerous, usually home but can only be killed early in the game, or if they are actively probing a pony (you can track this by reading the message about the Magician probing a pony's mind or checking the Day Screen). Recommend killing once able (as failing the Magician’s mini game can be game-ending). Once the Magician actually starts probing minds, they will usually do so every two days, so you can normally predict when they are vulnerable. If you get information that the Magician will be at another address, this actually means they are working and vulnerable, and conversely protected if they will be home.
Noble/Prince/Princess
Mostly harmless as Noble, but recommend killing once able if reasonable, normally home and unprotected. If killed, the Guard will become depressed and will either get lynched or commit suicide. If the Noble is left alive too long, they transform into the Alicorn, which is a combination Lookout, Sheriff, and Magician. The Alicorn can be a bit annoying but can be left alive for a bit. Can only be killed directly if the Princess tarot card is active (but the Guard can still stop you); alternately, recommend Death Letters or a cake. The Prince/Princess is often referred to as the Alicorn.
Guard
Mostly harmless, sometimes home, feasible to kill directly early in the game. Try to kill before they become active; ignore if you have killed the Noble/Alicorn. If a pony's eccentric behavior is noticed right after the Noble/Alicorn is killed, you know they are the guard. Note: After being thwarted by the guard three times you'll be visited by one of the investigators. If it happens a fourth time, you will be killed by them (rare, credit to SageExists).
Veteran
Extremely dangerous, always home, can only be killed directly very early in the game, or when they are known to be standing down. You should be scared of killing blindly in the mid to late game if you don’t know where the Veteran is (as getting shot usually leads to a game over). Kill by throwing suspicion if you cannot confirm they are standing down. Killing them is less important than avoiding them. If you get information that the Veteran is working, this means they are on alert, and conversely standing down if they are at home.
Lookout
Somewhat harmful, rarely home, difficult to kill directly, recommend killing if able. They will regularly thwart your plans if your luck is not high enough. The lookout can sometimes be invited to a private party, but otherwise you must throw suspicion their way later in the game.
Naturist
Harmless, always, home, cannot be killed directly under any circumstances. You must throw suspicion at them with letters or a cake to have them lynched (Death by Chocolate is unnecessary, cannot recommend).
Mayor
Mostly harmless, usually home, can normally be killed directly. Recommend killing later in the game, as they keep lynch mobs in check.
Visitor
Mostly harmless, rarely home, difficult to kill directly, and can mostly be ignored. The visitor usually gets lynched, or you they visit your house and you can kill them then. Rarely necessary to use any resources to kill.
Preacher
Mostly harmless, usually home while Changeling Spy is dead, and vice versa. Recommend killing later in the game, as having church as an option can be helpful. TIP: If the Preacher is with your intended victim, take note of the pony's name in the next day's newspaper, as this is free intel!
Deputy
Minor threat, rarely home, tricky to kill directly. Recommend killing when able, but preferentially kill other investigative roles if able. Can be killed directly when the Magician tarot card is active.
Sheriff
Moderate threat, rarely home, tricky to kill directly. Recommend killing when able, worth expending resources (letters/cakes). Can be killed directly when the Magician tarot card is active.
Detective
Moderate threat, rarely home, tricky to kill directly. Recommend killing when able, worth expending resources. Can be killed directly when the Magician tarot card is active.
Reporter
Mostly harmless if you consistently destroy evidence, sometimes home, somewhat tricky to kill directly. Don’t worry too much about killing them, unless given good opportunity, as they will usually get lynched.

The first two roles will appear as Townies, but are revealed once they die. The Mule can be a council member.
Disciple
Major threat if left alive too long, always home, easy to kill directly, but difficult to identify. Once a third of the town is dead, you want to start killing some Townies to try and kill the Disciple, or send your pet to investigate houses every day if you know their identity but not their address. Their rumors can be game-ending. The disciple cannot die to suicide and is less likely to be lynched than other townies.
The two main ways you can identify the Disciple are if they tell you they will be visited by the Preacher or Magician, as you can check the following newspaper or Magician's message, respectively, to get the name of the Disciple. While more niche, the same works with other visiting roles. If you know X role will be with the Disciple, and then you attempt to kill and are blocked by X role, you now know the Disciple's address (take note!).
Changeling Spy
Harmless, always home, easy to kill directly, but difficult to identify (can be identified with the Knave tarot card, but this process is a bit tedious). The Preacher will kill them eventually, but killing them gets you full info on two ponies, so it’s great if you get lucky and kill them, but it truly is luck.
Mule
Mostly harmless, no effect if killed directly. The mule is always an earth pony. If hanged, they will unleash a curse that will kill another pony. You cannot be killed, but your Sus will be maxed out if the curse targets you. Just good to know it exists.
Blackmailer/Ponies spreading rumors
The blackmailer is a pony who will try to spread rumors about you, and you are told their name eventually. You want to identify where they live and attempt to kill them ASAP, as their rumors can be serious dings to your Sus. Eventually you will get a message like the second one below, requesting money and giving you the street the blackmailer lives on, and at this point it is almost too late. The Blackmailer is worth expending resources to kill.
Undertaker
The Undertaker runs the morgue. You cannot send your pet to gather flesh or cutie marks if the Undertaker dies.
Mailpony
Keeping the Mailpony alive can trigger the Special Delivery event, which will give you a baking ingredient.
Party Planner
The Party Planner may eventually trigger the "Party Time" event, where they try to plan a party for the town on a set day in the future. If the Party Planner succeeds in throwing the party, your Bloodlust will be immediately maxed out, so you want to make sure to kill the Party Planner if "Party Time" triggers, or just kill them if given the chance.
Entertainer
The Entertainer can trigger the "Great and Powerful" event, where they predict who the killer is, and the town will lynch this random pony if given the chance. If the Entertainer is still alive after the lynching, this will trigger the "A Charlatan Exposed" event they are scolded for being wrong, and they become more Sus. I am not sure if this event can target you, but it is mostly harmless.

Cakes are generally most useful later in the game when the lynch mobs are consistent, but not always.
Moon Cake
Best used for roles that tend to be away from home, although there is some luck involved in being able to follow up with the kill that night. I bake and use other cakes before this one, if given the option. Does NOT work with Naturist or Magician.
Pound Cake
Best sent to a role that visits other ponies at night, such as the Sheriff, Deputy or Alicorn (Visitor technically, but usually the Visitor can be killed other ways).
Fruit Cake
Great for most roles that are difficult to kill, but it should only be used during the late game (active lynch mobs).
Sachertorte
Basically used the same as Fruit Cake.
Red Velvet Cake
The Veteran special. They have a chance to kill roles like the Lookout, Guard, Visitor and Alicorn.
Death by Chocolate
This tends to be a last resort, as you cannot make or send any other cakes after this one is used. Recommend only using for the Alicorn or an Investigative role if all three are still active later in the game.

These can happen multiple times per game.
Attending Church
It’s in your best interest to attend church every time. You can continue without clicking any holy prayers, and I would suggest only clicking prayers if you have Sus, and not if your sanity is already damaged. In the example below, it's worth clicking a prayer to try and clear your Sus.
Interrogated by the Sheriff, Detective, or Alicorn
You must click several circles. The number of red circles on the board is based on your luck. The circles are randomized, so don’t feel bad if you click wrong.
Interrogated by the Deputy.
You must click just one circle.
The Lookout/The Alicorn
I suggest only trusting your luck if it is 9-12, or if you desperately need to kill that night for bloodlust, or for an opportunity at a key target like the Magician, Alicorn, or an investigative role. Getting seen will not immediately increase your Sus, but you will be visited by at least one investigative role in the following days, which can increase your Sus.
Probed by the Magician/Alicorn
You must attempt to match the symbols blindly. This one frequently results in a game over, which is why the Magician and Alicorn are so dangerous.

These only happen once per game, at most. I’m only covering events that actually require you to make a choice, as the others just happen and are what they are.
The Visitor/Infested
It is almost always safe to kill a pony that enters your house. While there is a small chance the lookout saw them, it is worth it the risk (sometimes Infested is a council member!).
Rumors
This is Situational, as asking who they are talking about will add a Sus, but you will know who the Mule is. No effect if you mind your business.
The Preacher
Say you will attend church. As aforementioned, you can attend without any risk, and this reduces your Sus by one.
Target Practice
Do not sneak up on the Veteran.
Customer Service
This one is a bit situational. If you say yes, you will get the pony's address, and in larger towns it is usually a townie that you can get a free kill on. Saying no restores one point of sanity.
Slander
If two ponies tell you they think they know who the butcher of the town is, agree with them.
Happiness
This may be the only one that is situational. I believe saying yes may improve your reputation slightly at the cost of your sanity, but the second option will increase your Sanity with some risk.
Breakdown
If a pony has a breakdown in the streets and is in need of comfort, comfort them. This option reduces your Sus by one.
The Changelings
There are two versions of this depending on whether you kill the Changeling (shown first) or if the Preacher does (shown second). Either option works, but asking if they're going to bark all day or saying you need the Preacher alive are the options where you kill them (adds a Sanity, does not reset your bloodlust). The "Do as you will" option will result in the Preacher's death, which you may not want depending on how your run is going. This event will trigger if 2 Knave tarot cards are drawn after the Changeling Spy dies.
The Wages of Sin
If you attempt to kill the Mayor on Canterday night and he is in bed with another pony, kill them both.