Dodge lobbies until you find at least one Resident Evil character (preferably Chris, Sheva or Jill, but any will do just fine).

While waiting for a match, set up a 7 minute timer. You will need this timer for later. Start the timer as soon as you load into the match.

"Seven minutes. Seven minutes is all I can spare to play with you."

While in the game, tunnel any RE survivor (start with Chris, follow with Sheva, then the rest). Do not give them any chance to escape (bring chase perks to make sure they cant loop you, also bring a mori, you have to finish them off with a mori). You have to end the game within 7 minutes so make sure you tunnel everyone to get them out of the game early.
"Well then, I'll just have to kill you quickly."

After the game has concluded, type in post game chat:
"I expected more of a challenge after all this time, how disappointing."

If the game lasts one second more than 7 minutes (that's why you set the timer in the beginning), DC immediately, then type in chat the following:
"So you've made it this far... Too bad you won't make it much further."
along with:
"Seven minutes. Seven minutes is all I can spare to play with you."

If there is a Rebecca in the survivor team, you must let her escape or give her hatch by any means. You cannot down her or hook her, you can only hit her once but you must let her heal afterwards. Make sure she gets a lot of points by the end of the game, let her stun you, flashlight you and farm points off the rest of survivors (Wesker has a soft spot for Rebecca, considering he keeps a photo of her in his office, for... reasons).

You've reached the end of the guide! From now on, you are officially a Wesker main in DBD. Now go and do what Wesker mains do best!
It's Wesking Time!