There are mods that attempt to remedy this by enlarging the UI but still some elements are to small and the hotbar does not get fixed.
https://i.imgur.com/v53jRd3.jpg

1. Click on assets and download "nvidiaProfileInspector.zip 143 KB"
https://www.github.com/Orbmu2k/nvidiaProfileInspector/releases
2. Extract it using your flavor of archive manager (I use 7zip)
3. Launch

1. Upon launching Nvidia PI you will be greeted with this screen.
2. Use Profiles selector in the top left corner to navigate to Dragon Age: Origins

3. Change Antialiasing compatibility setting to 0x004010C0

4. Navigate to 3 - Antialiasing and change Antialiasing - Behavior flags to "None" and Antialiasing - Mode "Override any application setting"

5. My Anti Aliasing settings.

6. You can also use other anti-aliasing settings such as these.

These work too but they make the game too blurry so you would need some sort of sharpening (Reshade or Nvidia) to make it look good.

Open in browser and zoom in.
In-game anti-aliasing (8x)
https://i.imgur.com/d311Buh.png

Supersampling
https://i.imgur.com/dVwQ7El.jpg

In-game anti-aliasing (8x)
https://i.imgur.com/IDeZoQS.png

Supersampling
https://i.imgur.com/YG4lyeG.jpg

In-game anti-aliasing (8x)
https://i.imgur.com/vPOoKjy.png

Supersampling
https://i.imgur.com/1p3ZkxI.jpg

1. Opening Load Game Screen from Main menu causes it to flicker (which I can't for whatever reason capture it to showcase.) You can simply load the game from resume and load the save from there (might be a me only problem).
2. Some things like Nvidia fps counter or msi afterburner can be larger than it should.
You can set in-game antialiasing to 8x to counter it.
3. (Very minor) It breaks the Vignette effect and dialogue. Most (and barely) noticeable in the left upper corner when in dialogue or just walking around.