Who would have guessed that selecting easy mode made the enemies easier, right? Anyway here are some of the changes I noticed.

-You start with the Shotgun (The shotgun is not present in the village house)

-Enemy health is slightly reduced.

-Enemies will not run unless they are a significant distance from you.

-They throw weapons less often.

-You take less damage from hits and damage is consistent throughout the game due to the lack of dynamic difficulty.

-Enemies drop more health and ammo.

-The chances of causing Plagas Heads are lower.

-Quick-time events requires less inputs to complete. A LOT less inputs.

Additional Information from replies of this post

-"Shotgun shells stack to 25 and rifle ammo stacks to 20 on easy as well"

This is by far what changes the most on easy mode. A lot of areas are cut, important areas that I usually associated with when I am reminded of this game.

The Castle Gate key is not required to enter and the door that would normally be passed through to find it is "Blocked from the other side". Chapter 3-1

The section in the Maze garden with the caged dogs is completely bypassed. Chapter 3-2

Only the King's Grail is required to pass through the gate as the Queen's is already in place. This skips the section with the revolving door knights where the chest is in the middle. Chapter 4-1

You will only fight one Garrador at the section where you would normally fight two. Chapter 4-1

Dr Salvador (chainsaw man) is not present in the Mines where you would use dynamite to blow up the rock Chapter 4-3

The section where you would normally be trapped and have to shoot the red lights has also been removed. Chapter 4-3

The bridge section on chapter 4-1 the one where you have to destroy the blocks of wood blocking the gears to operate it, This is completely skipped, just like the Maze section. This scene is also interesting as it uses a pre rendered cutscene from the PS2 version. Enemies are also not waiting outside the entrance to the next section of the game

Minor edits to fix spelling mistakes, grammar and structure.