The main story can be roughly divided into five parts:

1) Meet everyone you can.
2) Go to the sexworld and check out the differences. (= Seek out every character again.)
3) Watch the aftermath and to figure out what is going on. (= Talk to every character a 3rd time.)
4) The office questline. (Mostly inear and self-explanatory.)
5) Exploring the sexworld again. (Explore the town a fourth time.)

Part 3 is a bit more complicated than that, but this is the basic structure. Basically, the easiest way to get stuck is to miss a character you need to talk to, therefore I’ve compiled this list for easy checking.

Warning: The hint system does not tell you the correct hints during part three. It will tell you to return home before you can actually proceed at home. Instead, you may have to talk to several more people. The last person you actually talk to in part three is Edward in front of the school.


The game often doesn’t tell you when you have reached the current end of the main story.


End of Update:
v0.30:
Current end of update is when you are asked to go around and talk with everyone a third time in order to find out what is going on. You can talk to some people but most of it is not implemented. I think the last person you talk to is Effie.

v0.32:
Part 3 has been expanded to include most characters. The endgame is now going through your first day at the office, which should be completely linear. I won’t include the new characters yet because you don’t need them for anything.

v0.38:
Endgame is now playing three (incomplete) minigames for the first time, then talking to the CEO again.

v0.40:
Main story ends after talking to Edward in the forest. You will probably not get that far due to a severe save file breaking bug.

v0.46:
Main story ends after returning to the sexworld for a bit.

Misc:

Jane, Mrs. and Mr. Smith, Jacob, Effie, Allaway, Dir. Lashley and Jack should all be unavoidable unless you ignore the main story hints.

Janae, Alanna and Grundle Sam work at the mall.

Brock: Talk to him at the gym at night then again at the cafe whenever Effie is not there.

Violetta: Beach (Random encounter if you go jogging.)

Houses on the top right part of the map:
Effie’s dad: upmost, rightmost house but only very rarely. (I think on the weekends, but try at other times if not there.)
Jacob’s dad + Lailah: topmost row, directly left of Effie’s house. May need to check it at various times to get both.

University:
Meghan, Chieghan, Teghan = Female bathroom in the morning (Bonus Meghan scene Friday afternoon)
Edward: In front of school in the day, at the beach at night
Cole: School cafeteria (morning)
Zariah: Downstairs school hallway (afternoon) ←Necessary in order to visit nightclub
Jaiden: gym (morning)
Luna: Upstairs school hallway (morning) or classroom (afternoon)
Phil: School bathroom (morning)
Coach Fistem: Gym (night)

Street to the south:
Hitomi: Leftmost door (comic book store) (Bonus Hitomi scene at the beach on Saturdays)
Kevlamin, Crugeon, Davendithas: Comic book store, back room.
Hazel: Middle door (sex shop)
Steve: Rightmost door (nightclub). Only accessible at night after meeting Zariah