This achievement is very broken and required me throwing 150 bombs before it triggered, at Brax and then at the Dread collectors that spawned, though I'm not sure how relevant that is.

For this the fastest way to trigger the achievement is to use -debug-flag as a launch option (picture below), which will open the game in debug mode and make this a lot faster.

To be able to fast craft The Bomb you will need to take the following three skills when you start

• Wand Lore
• Rogue Scientist
  
• Communist

The other 4 skills are irrelevant

Start the game and press the letter L on your keyboard, which will level you up because we are in debug mode. Assign skill points to max out Wand Lore, Rogue Scientist and Communist. You will have to close the skills tab and press L again to get enough skill points to max all three.



Now go into your inventory and open the n-Dimensional Lathe and scroll to the bottom of the crafting page to The Bomb

While in debug mode clicking on crafting ingredients will add them to your inventory, so click on all 4 of the crafting ingredients and craft as many bombs as you think you will need.



Now save the game and right click on The Bomb to equip it as a weapon and find some enemies to throw the bomb at. If the achievement doesn't trigger, reload the save and find some other enemies to nuke.

Have fun, and remember to throw the bomb at least 6 squares away from you, otherwise you'll be hit by the fallout.