This fix actually worked for me under Windows 7 (and 10), whereas the other "fixes" I found did not. Go to http://www.wsgf.org/dr/prototype and look under the Solutions & Issues section. From there, download "Prototype_All_Res.zip." !!! See updates section below for current download locations !!!

Backup "prototypeenginef.dll" and replace it with the file inside the zip. The original file is located in C:\Program Files (x86)\Steam\steamapps\common\Prototype. This will set your game resolution to whatever your Desktop is set to.

You may or may not be able to change your video settings ingame anymore after using this fix, but you can, if necessary, still set your AA and AF through the Nvidia Control Panel.

Hope this works for you! Prototype is an awesome (if very underrated) game!


NOTE: This fix is for the resolution bug in Prototype. It isn't meant for fixing general crash issues. However, BioEvilCat has this tip for those experiencing crashes on modern hardware:
"After doing all file processes (ie, applying the fix described above), open TASK MANAGER --> DETAILS tab --> and go to the STEAM.EXE process. Set its affinity to only FOUR cores and hit okay. PROTOTYPE 1 is optimized to run on processors with 4 cores down."
BioEvilCat was suffering crashes on a 12 core CPU and setting the affinity to only 4 seems to have fixed their problem.


The original file link is down. Thanks to Steam user Shaidon, it is currently hosted at:
https://mega.co.nz/#!29MjlYRa!qt2ai0-ofJQgqbvnB1UXNjOhATlz4cPhR9FAXj4To7o

This fix was originally for Windows 7, but some Windows 10 users have reported that it has worked for them, as well.

As of this date, the original Wsgf.org page again has links for where the fix can be found, but still no direct download links.

The Mega download link from 2015 still works for the original fix.

This page has a direct download link to what I believe is a more recent version of the fix: https://community.pcgamingwiki.com/files/file/1486-prototype-resolution-and-fov-fix/ .

I've long since upgraded to Windows 10, and can confirm that the fix currently found at pcgamingwiki.com works for me!