We begin with a very popular combo. Chaos Monday. The combination of Chaos Butterfly and Essence of Monday is probably infamous by this point, increasing the accuracy of the bullets, keeping them on screen longer, and boosting the damage output of a single bullet to insane levels. The longer we can keep bullets around, the better.

Second step, multiply projectiles. Two of the best items for this are Seashell and Spider Silk. While I cannot confirm 100%, it seems like the damage decrease from both are largely mitigated, as they seem to be a percentage of the damage the bullet they split from was at. So, if a bullet reached around 500 damage, when it splits, the bullet would be around 375 or 100, depending, which would themselves multiply in power.

Third, making sure projectiles actually hit. This means they need to avoid walls, and ideally be able to hit an enemy more than just once. I personally use Bouncy Ball and Diamond, though Trick Bullet and Rock are good substitutes.

Finally, making sure the projectiles actually hit. The obvious choice for this is Crystal Ball. This ensures that your projectiles will swarm your target, increasing in DPS over time up to a peak of around 25k, more or less. Interestingly, you can also swap Bouncy Ball for Mini Sun and set to an enchantment for roughly the same DPS, minus maybe 5k tops and some practicality. So just slap all this on your wand and go to town!


...Wait, did you say wand!? I sure did! This bad boy does a whopping 25k without even needing to spend mana! But if you REALLY want things to die, make it a spell. Any boss barring the temple ones will be absolutely floored by it. While it may be overkill, it's just the right sort of overkill I like to reserve for my spell so that my wand can use some nice offensive utility magic. So go to town with your brand new 250,000 DPS spell!