On the Wii, power was a major problem. Games could only run at 480p and had technical limitations such as the controller and the graphics card. They solved this in the original by using render fog to obscure the loading of objects from view. https://youtu.be/LgPtEXScOqY You can really see how the game looked on the Wii compared to the PC in this video.
The game also had a pixel smudge effect stop the game from looking pixelated. On the PC, both of these were removed even though the game's loading remained the same!

The most noticeable change for me was that the game uses a different icon for the art pieces. In the original game the art pieces looked like Ginger's head on a book but in this game they are sheets of paper. https://youtu.be/voB3TyH-Mrc In addition all the art pieces are the American competition's pictures. This means that there are a completely different set of drawings!

Some of the dialog in the game is altered as it once again uses the American version for reference.
Also, some sound effects such as several character's voice clips are removed, so during conversations with multiple characters, it can be hard to tell who is talking.

I have the PAL version of the Wii title and I can tell the game plays faster.
The PAL game is slower than the American game and some of the enemies are harder due to moving faster because of the frame rate.
NEVER play on 60 FPS as it makes some chasing enemies UNSTOPPABLE!