Two rounds of Soviet purges directed by Moscow (1927–1934 and 1937–1938) resulted in the expulsion of nearly 10,000 people, from all levels of the Communist Party of Tajikistan.[24] Ethnic Russians were sent in to replace those expelled and subsequently Russians dominated party positions at all levels, including the top position of first secretary.[24] Between 1926 and 1959 the proportion of Russians among Tajikistan's population grew from less than 1% to 13%.[25] Bobojon Ghafurov, Tajikistan's First Secretary of the Communist Party of Tajikistan from 1946–1956 was the only Tajikistani politician of significance outside of the country during the Soviet Era.[26] He was followed in office by Tursun Uljabayev (1956–61), Jabbor Rasulov (1961–1982), and Rahmon Nabiyev (1982–1985, 1991–1992).

In 1924, the Tajik Autonomous Soviet Socialist Republic was created as a part of Uzbekistan, but in 1929 the Tajik Soviet Socialist Republic (Tajik SSR) was made a separate constituent republic; however, the predominantly ethnic Tajik cities of Samarkand and Bukhara remained in the Uzbek SSR. Between 1927 and 1934, collectivisation of agriculture and a rapid expansion of cotton production took place, especially in the southern region.[23] Soviet collectivisation policy brought violence against peasants and forced resettlement occurred throughout Tajikistan. Consequently, some peasants fought collectivisation and revived the Basmachi movement. Some small scale industrial development also occurred during this time along with the expansion of irrigation infrastructure.[23]

After the Russian Revolution of 1917 guerrillas throughout Central Asia, known as basmachi, waged a war against Bolshevik armies in a futile attempt to maintain independence. The Bolsheviks prevailed after a four-year war, in which mosques and villages were burned down and the population heavily suppressed. Soviet authorities started a campaign of secularisation, practising Islam, Judaism, and Christianity was discouraged and repressed, and many mosques, churches, and synagogues were closed. As a consequence of the conflict and Soviet agriculture policies, Central Asia, Tajikistan included, suffered a famine that claimed many lives.

It is, however, only in accordance with supreme justice if those interests are also taken into account that are founded upon ethnographical, historical, or economic conditions.

I can assure you that I look into the future with perfect tranquillity and great confidence. The German Reich and its allies represent power, military, economic and, above all, in moral respects, which is superior to any possible coalition in the world. The German armed forces will always do their part whenever it may be necessary. The confidence of the German people will always accompany their soldiers.

The Danube as an important waterway is thus safeguarded against any further act of sabotage. Traffic has been resumed in full.

Apart from the modest correction of its frontiers, which were infringed as a result of the outcome of the World War, the Reich has no special territorial interests in these parts. As far as politics are concerned we are merely interested in safeguarding peace in this region, while in the realm of economics we wish to see an order that will allow the production of goods to be developed and the exchange of products to be resumed in the interests of all.

Churchill, one of the most hopeless dabblers in.strategy, thus managed to lose two theaters of war at one single blow. The fact that this man, who in any other country would be court-martialed, gained fresh admiration as Prime Minister cannot be construed as an expression of magnanimity such as was accorded by Roman senators to generals honorably defeated in battle. It is merely proof of that perpetual blindness with which the gods afflict those whom they are about to destroy.

The consequences of this campaign are extraordinary. In view of the fact that a small set of conspirators in Belgrade again were able to foment trouble in the service of extracontinental interests, the radical elimination of this danger means the removal of an element of tension for the whole of Europe.