The Meme Machine (2000) is a popular science book by psychologist Susan Blackmore on the subject of memes. Blackmore attempts to constitute memetics as a science by discussing its empirical and analytic potential, as well as some important problems with memetics. The first half of the book tries to create greater clarity about the definition of the meme as she sees it. The last half of the book consists of a number of possible memetic explanations for such different problems as the origin of language, the origin of the human brain, sexual phenomena, the internet and the notion of the self. These explanations, in her view, give simpler and clearer explanations than trying to create genetic explanations in these fields.

The idea of memes, and the word itself, were originally speculated by Richard Dawkins in his book The Selfish Gene although similar, or analogous, concepts had been in currency for a while before its publishing.

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