Monday
When the Postal Dude goes to the RWS headquarters on Monday, he is informed by Vince Desi that he's fired. This and an anti-video game protest mob by the Parents for Decency began his second reign of terror. After getting his paycheck, the Dude then proceeds to go to cash the check in the Fee of America bank. Just as the Postal Dude is cashing his check, a group of bank robbers arrives to commit a stick-up. However, if the Dude breaks into the money bin to get the money from there, an alarm will sound and he will have his first clash against the Police. After cashing his check, the Postal Dude goes to Lucky Ganesh to get some milk. Once he returns home, the Dude informs his wife that he's "on sabbatical", so she decides to get him to do more errands for her for the rest of the week.

Tuesday
On Tuesday, the Postal Dude decides it's time to confess his sins, so he goes to the Church to be forgiven by a priest. Meanwhile, a group of Al-Qaeda terrorists arrive and commit their attack, breaking into the Church, so the Dude must face a large group of them in order to escape. After that, the Postal Dude must get eight signatures for a petition to "make whiny congressmen play violent video games", which makes him deal with lots of rude civilians and prompts him to threaten them if they refuse to sign. The Postal Dude must then go to the Library to return a book his wife has been reading. However, once he has returned it, a group of book protestors break into the library, burn the building down, and attack everyone within it, including the Dude. He must find himself a way out of the library and fight many book protestors. Finally, he has to go to the Paradise Mall, where Gary Coleman has arrived to give away autographed copies of his book. Once there, the Postal Dude gets his copy. Suddenly, the Police arrives to arrest Gary, initiating a fight against him and his crew.

Wednesday
On Wednesday, the Postal Dude decides to go to the Cemetery and piss on his father's tombstone. When he does so, the Dude is knocked unconscious by a group of rednecks who take him to their Brewery. When the Postal Dude wakes up in the Brewery, he realizes the rednecks have removed his own clothes and made him wear a Gimp Suit, so the Postal Dude adds one more errand that is going to Money Shot Laundromat to pick up his laundry. After fighting a large group of rednecks and getting out of the Brewery, people everywhere make fun of him until he gets his clothes back. Wednesday is also Election Day, and ♥♥♥♥ Asian is hosting the elections. Also during Wednesday, the Dude goes to the Forest to get a Xmas Tree. Given that it's July, the trees are much cheaper. After looking at several trees, the Postal Dude finally chooses the right one, but summons rednecks to attack him once more.
Thursday

On Thursday, the Postal Dude notes that the weeds in his garden are getting too tall, so he needs something extra strong and decides to buy a Napalm Launcher at the Napalm Factory. Once he manages to get the launcher, a factory worker vomits on a power box presumably operating the machinery at the factory, causing a major disruption in the production process, resulting in a major explosion that destroys part of the factory. The Dude must find a way to get out of the factory via alternative ways. Also on Thursday, Krotchy has arrived at Paradise Mall, so the Dude must get a Krotchy Doll. When he arrives at Toyz 'n tha Hood, Krotchy tells him that all of the available Krotchy dolls are sold out, but the Postal Dude breaks into the store's back room anyway, and manages to get a doll from the storage. This calls the Police into the store in an attempt to arrest him. After defeating the police and getting out of the back room, the Postal Dude has to confront Krotchy himself. During that same day, the Postal Dude wants to get some steaks for the Psychotic Friends Network Barbeque he's planning to attend, so he goes to Meat World. However, there is no one attending in the butchery, so he goes to the backroom, where he discovers some Butchers triturating people alive in a grinder. The butchers attack the Postal Dude for discovering them and entering into the backroom. Once the Dude gets the steaks, the police enters the place and tries to arrest the Dude again for trespassing. Finally, the Postal Dude must go to the Police Station to pay a Traffic Citation. Eventually, he returns to his Trailer and fires the Napalm Launcher at the carpet.

Friday
On Friday, the Postal Dude goes to the Junkyard to get an alternator to fix his broken car. Once he gets the alternator, a tower crushes a fence containing some dogs, blocking the exit and letting the dogs out which attack him until he exits the junkyard. On the same day, he gets a note that says there is a package for him, so he goes to the Parcel Center. However, when a carrier gets it for the Dude, it explodes, making the carriers attack the Dude in retaliation. Friday is also Uncle Dave's birthday, and the Postal Dude wants to give him a Birthday Gift, so he proceeds to go to the Compound, where Uncle Dave's "party" is taking place. The "party" is revealed to be the siege of the compound by the ATF. The Postal Dude manages to enter the compound and give Uncle Dave his gift, and in that very same moment the ATF finally manages to break into the compound, starting a massive gunfight against the Dude and Uncle Dave's religious cult. Since the beginning of Friday, the Postal Dude wants to desperately piss, and when he does so, it hurts, so he decides to go to the Clinic. Once there, the nurses tell him he has gonorrhea, and tell him to go and see Vend-A-Cure, a machine that after receiving a piss sample from the Dude, gives him some Gonorrhea Medicine to cure him.

After completing all the errands of Friday, the Paradise Times releases a special edition that announces the beginning of Apocalypse. During the Apocalypse, there is a sudden outbreak of violence and all people in Paradise are armed, fighting each other, and will immediately attack the Dude even if he isn't carrying a weapon. After the Dude manages to go back to his trailer, the ♥♥♥♥♥ asks him if he remembered her Rocky Road, an item she requested him to get for her since Monday, but that was never included as an errand. The Postal Dude then proceeds to shoot himself in the head so he can stop hearing her nagging.