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But in reality that's usually what it takes.
Nuclear weapons were invented in 1945, but it took until the 60s (and a lot of close calls) for effective regulation to be implemented. If you lived in that time and were in the know, moving from simple fission weapons, to thermonuclear devices 1000x as powerful as Little Boy, to doomsday projects like Pluto and Sundial must have made it seem like the world was about to end.
But, in the end, rationality triumphed over the lure of power.
Once enough tragedies or enough harm (or potential harm) is done, then there's national govt type of regulations. I.e. leaded gasoline took a while to get regulated, despite the blatant harm it caused.