I just now started having the same problem. Have no idea. My IT skills are in healthcare, not gaming.

Sounds a bit like either a savegame or mod issue. Do you play with mods? If so, that might be what's caused it. I had a similar thing happen with Fallout 3, which is also Bethesda made - using mods.

My advice is to check your savegames folder
C:\users\*yourusername*\documents\my games\skyrim\saves

and make sure your saves are still under or around 10-12 MB in size. Under that is fine also. If they're larger then either you've put ~450 hours into your character or a mod is bloating the savegame and causing your crashes (which will likely mean you'll have to track down the faulty mod and remove it, and those savegames might well be wrecked. It's not too likely recovering them from that kind of error, unfortunately, though maybe people in the skyrim forum might be able to help you there)

Hopefully it'll be something else other than this, cause it can be a pain in the A**

Originally posted by stormvet:

Everytime i try to save, whether its a quicksave, autosave from resting, or saving from the escape menu my game crashes. I just did that steam upload to "improve" it and now my game is basically unplayable as I cant save. Anyone have any suggestions on how to fix this. Im an old fart so dont get too computer techish on me please.

First, crack open a window. Second, I can't help with the rest.