No discussions here addressed fixing running Omikron on Windows 11 so here is how I got mine to play -

Download the latest dgVoodoo 2.
I used this link : https://dege.fw.hu/dgVoodoo2/dgVoodoo2/

Extract dgVoodooCpl.exe, dgVoodoo.conf, D3DImm.dll and DDraw.dll and add files to game directory.

Open dgVoodooCpl.exe, go to DirectX, Select Virtual 3D Accelerated Card under Videocard, I selected 256 VRAM. Click Apply and OK.

Now run runtime.exe

This fixed running the game when compatibility changes were doing nothing (as previous suggested).

UPDATE-
In the game menu I was able to select 4K resolution, now on my HDR monitor Omikron looks SO GOOD, wow I'm excited to play through this CLASSIC nostalgic game!! Definitely want to attend all the Dreamers concerts this time +_+

Anyone find any easter eggs in this game?

Hope this works for you if you are having trouble starting in Windows 11.