I've done "cripple movement" constantly to keep her in place and then emptying my Satara shotgun into her (might have made her burn with Psalm 11:6 assault rifle, but that's pretty much it). And yes I play with the hardest level so it works there too

First; Sneak around the edge of the "arena", and take her mallet when she's not looking. She'll only run to grab it when you enter combat, so make sure you stay out of it. That will reduce the amount of damage she can do instantly.
(I *think* a recon grenade will make her "search" for it, so that might help. She may not care about it though, as it appears some enemies don't.)

Second; Cripple movement hack, as above.

Third; Contagion hack + an explosive/thermal weapon. Comrade's Hammer would be a good pick -> big damage + high chance of ignition, plus you can always smack her with a melee attack for the quick reload. Or Psalm as Aqu above said. There are other weapons too, but the Contagion quick hack is ignited by a fire/thermal weapon, so anything that can ignite enemies is a potential.

I done her last night. blocked her and hit her hard with the cane from fingers (the pervy
creepy ripperdoc)
she dropped her hammer and I quickly picked it up and then kept smacking her with the cane till she had enough.

Cripple movement hack between tier 4 and 5, is very OP (even against Adam Smasher). Try using that on her and unload your weapon attacks while zipping around, kiting her launch hammer attacks.

Don't know what your RAM regen perks look like, but if it's fairly quick, you should be able to rinse repeat this, without her getting one hit on you.

The way I did it on very hard difficulty: cripple movement hack stacked with cyberware malfunction + a steady stream of lead in her head, with a smart weapon (stacks damage with cyberware malfunction hack) hitting high crits to tear her health down faster.
As most of us know, very hard also = very bullet spongy.

Good luck, have fun!

I just snuck around her lol

I'm on my second playthrough and I had a weird encounter with her a few days ago. I don't know if this was a bug, a feature, or coincidence but as soon as I put a second stack of T3 disable cyberware on her, she completely shut down and stopped attacking altogether.

Other than that, instead of trying to kite her around staying out of range of her hammer, just parry it. Her biggest weakness is her attack speed which makes her incredibly easy to parry. Equip the strongest melee weapon you have, parry her, and when she's momentarily stunned slip around and hit her a few times from behind. Or if you have a decent swap speed, then swap to your gun shoot her a few times then swap back to your melee weapon.

Originally posted by Sausage Fingers:

I just snuck around her lol

Going this route will have an effect to a later mission if you have Phantom Liberty. It will have something to do with Aaron's quest line later in the game, should you want to try a certain outcome.

Originally posted by Axetwin:

I'm on my second playthrough and I had a weird encounter with her a few days ago. I don't know if this was a bug, a feature, or coincidence but as soon as I put a second stack of T3 disable cyberware on her, she completely shut down and stopped attacking altogether.

Other than that, instead of trying to kite her around staying out of range of her hammer, just parry it. Her biggest weakness is her attack speed which makes her incredibly easy to parry. Equip the strongest melee weapon you have, parry her, and when she's momentarily stunned slip around and hit her a few times from behind. Or if you have a decent swap speed, then swap to your gun shoot her a few times then swap back to your melee weapon.

That's a bug. It happens every once in a while. It happened on my third replay. I had to reload the boss fight for it to be fixed. Didn't freeze up again. This has been reported for some time now, but unfortunately has not been addressed yet.

I did take a bunch of fun screen shots while Sas was frozen in place, though. lol

Originally posted by Nar!:

Originally posted by Axetwin:

I'm on my second playthrough and I had a weird encounter with her a few days ago. I don't know if this was a bug, a feature, or coincidence but as soon as I put a second stack of T3 disable cyberware on her, she completely shut down and stopped attacking altogether.

Other than that, instead of trying to kite her around staying out of range of her hammer, just parry it. Her biggest weakness is her attack speed which makes her incredibly easy to parry. Equip the strongest melee weapon you have, parry her, and when she's momentarily stunned slip around and hit her a few times from behind. Or if you have a decent swap speed, then swap to your gun shoot her a few times then swap back to your melee weapon.

That's a bug. It happens every once in a while. It happened on my third replay. I had to reload the boss fight for it to be fixed. Didn't freeze up again. This has been reported for some time now, but unfortunately has not been addressed yet.

I did take a bunch of fun screen shots while Sas was frozen in place, though. lol

I was hoping for it to be a feature but expecting it to be a bug. lol

But honestly, while it made the fight a lot faster, I didn't need it. All the bug did was expedite the fight but I was handedly winning regardless because like I said, she is insanely easy to parry.

Originally posted by moonlightavenger:

Some old advice tells you to short circuit her, and it is supposed to break her crystal thing that keeps healing her. It doesn't. Also, scanning her adds no advice. Even if I break that thing during the fight she does so much damage, and I do so little it's not even worth it. What am I missing?

i always favor a stun baton for that fight, double tap dodges around her ...like the pool cue fight in shawn of the dead :P

She can't find any path around obstacles in the room and basically stun locks herself by dashing against the boxes and pillars. Just cheese it. She's ridiculously OP for being so early in the game.